围绝经期肥胖患者154例中医证素分布特点研究

Study on distribution characteristics of TCM syndromes in 154 perimenopausal obesity patients

目的:通过对女性不同年龄阶段的肥胖及围绝经期肥胖与非肥胖的证素分布特点的分析,找出围绝经期肥胖主要的病位、病性证素分布特点,为临床治疗围绝经期肥胖提供客观化理论,并为临床上围绝经期肥胖的中医病理深入研究提供依据。方法:应用证素辨证原理,选择育龄期肥胖、围绝经期非肥胖、围绝经肥胖的3组女性,分析中医证素分布特点。结果:围绝经期肥胖以中心性肥胖为特点;围绝经期肥胖与育龄期肥胖比较,在肝、肾、心以及气滞、血虚等证素上具有显著差异(P<0.05),在痰、湿、脾证素上无差异性;围绝经期肥胖与围绝经期非肥胖组比较,痰、湿、脾等证素具有显著差异(P<0.05);围绝经期肥胖组病位证素的频数及积分前3位为肝、肾、脾,实证病性为痰、湿、气滞,虚证病性为阴虚、气虚、阳虚。结论:脾、痰、湿证素是肥胖的特征性证素;围绝经期肥胖多数以中心性肥胖为特点,肝、脾、肾、痰、气滞、阴虚是特征性证素。

Objective: To analyze the distribution characteristics of obese women and obese menstrual obesity and non-obesity in women at different ages, and to find out the distribution characteristics of obese menstrual obesity and the distribution of pathogenic syndromes, and to provide objective theories and a basis for in-depth study of TCM pathology of perimenopausal obesity. Methods: Patients with obesity, perimenopausal non-obesity, and perimenopausal obesity were selected to analyze the distribution characteristics of syndromes in traditional Chinese medicine. Results: Perimenopausal obesity was characterized by central obesity. Perimenopausal obesity was significantly different from liver, kidney, heart, qi stagnation,and blood deficiency syndrome in comparison with obesity at childbearing age(P<0.05). There was no difference in phlegm,dampness and spleen(P<0.05). The perimenopausal obesity was different from that of the perimenopausal non-obesity group in terms of phlegm, dampness, and spleen. The frequency of epilepsy and the top three points in the obese menopausal group were liver, kidney and spleen. The excess syndromes were phlegm, dampness, qi stagnation and the deficiency syndrome were yin deficiency, qi deficiency, yang deficiency. Conclusion: Spleen, phlegm, and dampness syndrome are the characteristics of obesity.Perimenopausal obesity is mostly characterized by central obesity. Liver, spleen, kidney, phlegm, qi stagnation, and yin deficiency are characteristic evidence.