基于证据探讨老年人腹主动脉瘤筛查

Evidence-based screening for abdominal aortic aneurysms in elderly

腹主动脉瘤是最常见的动脉瘤，其特征为无明显临床症状，易发生瘤体破裂，死亡率极高。使用超声筛查能够实现早期诊断，降低瘤体破裂导致死亡的风险，然而，在筛查过程中常存在一些不良后果，如患者心理困扰，治疗带来的间接伤害等。腹主动脉瘤的发病率也存在明显的年龄和性别差异，因此合理有效的筛查策略尤为重要。本文检索腹主动脉瘤临床试验，系统评价、Meta分析，筛查指南，以期得到合理的筛查策略。

Abdominal aortic aneurysms（AAAs） is the most common aneurysm, and usually characterized by less symptom. While ruptured AAAs leads to high mortality. Abdominal ultrasonography can effectively detect AAA, decrease the AAAs-related mortality. However, screening AAAs causes some adverse outcomes, including psychological distress and immediate harms in treatment. Meanwhile,the prevalence of AAAs in sex and age is significantly different. Therefore, a reasonable and effective screening strategy is very important. This article search random control trials, systematic reviews, meta-analysis and guidelines in screening AAAs to obtain a reasonable screening strategy.