离子刀配合中药熏洗治疗高位单纯性肛瘘临床研究

Plasma knife combined with fumigation of Chinese medicine for patients with high simple anal fistula:a randomized controlled trial

目的评价离子刀配合中药熏洗治疗高位单纯性肛瘘的临床疗效。方法纳入2015年9月至11月期间到成都中医药大学附属医院肛肠科就诊,且符合高位单纯性肛瘘诊断并同意自愿参与本试验研究的患者62例,采用随机数字表将患者随机分到治疗组（离子刀组32例）和对照组（挂线组30例）。治疗组患者采用等离子刀手术治疗机治疗,对照组采用传统挂线手术治疗。入组前3天进行患者手术前评估和基线期评价,手术治疗及术后护理2-3周（治疗期）进行评价,入组后3月进行电话随访。结果两组患者经治疗后治愈率均为100%,而治疗组的术后疼痛程度评分（VAS评分）显著低于对照组（2.32vs.4.89cm,P=0.002）。治疗组患者的创面愈合时间显著少于对照组（19.31vs.28.72天,P=0.001）。结论离子刀配合中药熏洗治疗高位单纯性肛瘘能明显减轻患者术后疼痛和创面愈合时间,值得临床推广应用。

Objective To evaluate the effectiveness of plasma knife combined with fumigation of Chinese medicine on patients with high simple anal fistula.Methods We included 20 patients visited teaching hospital of Chengdu university of traditional Chinese medicine and were diagnosed with high simple anal fistula.These patients were randomly divided into experimental group treated with plasma knife and control group treated with cutting section and drainage suture selective operation.The patients were evaluated at baseline,at the end of treatment and 3months after treatment.Results Patients in the 2groups were cured（response rate 100%）.VAS score in the experiment group was significantly lower that in the control group（2.32 vs.4.89 cm,P=0.002）.And the time to wound healing in the experimental group was significantly shorter than that in the control group（19.31 vs.28.72 days,P=0.001）.Conclusion Plasma knife combined with fumigation of Chinese medicine can reduce postoperative pain and time to wound healing,which deserves recommendation in clinical practice.