2型糖尿病合并脑梗塞的危险因素分析

The Analysis of Risk Factors in Cerebral Infarction with Type 2 Diabetes Mellitus

目的探讨2型糖尿病合并脑梗塞的危险因素。方法对201102-201412期间的2型糖尿病合并脑梗塞患者100例及2型糖尿病无脑梗塞的120例进行临床资料的比较,包括年龄、BMI、HbAlc等进行比较。结果糖尿病合并脑梗塞组年龄、吸烟史、收缩压、甘油三脂、胆固醇、空腹及餐后2 h血糖以及糖化血红蛋白明显升高。为排除各因素的相互作用,以脑梗塞发病与否为应变量,其他因素为自变量,行logistic回归分析,结果表明餐后2 h血糖、收缩压、年龄差异有统计学意义。结论年龄、收缩压、餐后2 h血糖为糖尿病合并脑梗塞的最危险因素。

Objective The purpose of this study was to assess the risk factors of T2 DM with cerebral infarction.Methods In the case control study,100 T2 DM patients with cerebral infarction were selected as T2DM＋ cerebral infarction group and 120 T2 DM patients without cerebral infarction as control group,age,BMI,HbAlc et al were measured in all patients.Results Age,history of smoking,systolic blood pressure,TG,FBG,HbAlc P2 hBG were higher in patients with cerebral infarction than control group.In order to eliminate the interaction among the factors,using cerebral infarction as dependent variable and other factors as covariates,multiple logistic regression analysis suggested the P2 hBG,age,systolic blood pressure,were significantly associated with cerebral infarction.Conclusions age,systolic blood pressure,hyperglycemia were strong risk factors of cerebral infarction in type 2 diabetes mellitus.