哮喘儿童呼出气一氧化氮与肺功能的相关性分析被引量：3

Correlation analysis between exhaled nitric oxide and lung function in children with asthma

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摘要目的分析儿童哮喘的呼出气一氧化氮（Fe NO）水平和肺大小气道功能的相关性,以明确Fe NO对于哮喘气道阻塞的诊断价值。方法收集2014年6月至2015年10月在我院哮喘专科门诊确诊为支气管哮喘的4~18岁患儿560例,均进行Fe NO和肺功能检测。肺功能指标包括：大气道功能,包括1秒用力呼气量（FEV1）、用力肺活量（FVC）、峰值呼气流速（PEF）;和小气道功能,包括用力呼出25%肺活量时呼气流速（FEF25）、用力呼出50%肺活量时呼气流速（FEF50）、用力呼出75%肺活量时呼气流速（FEF75）、最大呼气中段流量（MMEF）。分析Fe NO值和肺功能各项指标的相关性。结果 560例哮喘儿童Fe NO值为（25.60±21.00）ppb,与肺功能各项指标FEV1、FVC、PEF、FEF25、FEF50、FEF75、MMEF皆存在线性负相关（均P〈0.05）。结论儿童哮喘的Fe NO水平与肺功能及小气道功能受损相关,可反映儿童哮喘的气道阻塞程度。

作者张家伟孟帅徐小评

机构地区成都市第二人民医院儿科

出处《实用医院临床杂志》 2016年第3期119-120,共2页 Practical Journal of Clinical Medicine

关键词呼出气一氧化氮肺功能小气道功能哮喘儿童

分类号 R562.25 [医药卫生—呼吸系统]

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