碳酸氢钠联合肝素钠封管对深静脉导管堵管的影响

Effects of sodium bicarbonate and heparin sodium sealing on deep vein catheter blocking

目的：探讨碳酸氢钠联合肝素钠封管预防深静脉导管堵管的临床效果。方法：选择2014年1月-2015年6月我科收治的200例重症患者,随机等分成试验组和对照组,试验组用5%碳酸氢钠250 ml＋肝素钠6250 U,每次抽取10 ml封管液,每6 h脉冲式正压封管1次;对照组用生理盐水250 ml＋肝素钠6250 U,每次抽取10 ml封管液,每6 h脉冲式正压封管1次,观察两组患者深静脉导管的留置时间、堵管情况。结果：试验组深静脉导管的留置时间长于对照组,堵管情况低于对照组,差异均有统计学意义（P〈0.05）。结论：碳酸氢钠联合肝素钠进行深静脉封管,可以有效延长深静脉导管的留置天数,降低深静脉导管的堵管率。

Objective： To explore clinical effects of preventing deep vein catheter blocking by using sodium bicarbonate and heparin sodium sealing. Methods： Randomly divided 200 critical cases January 2014 to June 2015 cured in our department into experimental group and control group. Used 250 ml 5%sodium bicarbonate and 6250 U heparin sodium for experimental group,extracted 10 ml tube- sealing fluid each time and conducted pulsed positive pressure sealing once every 6 h. Used 250 ml normal saline and 6250 U heparin sodium for control group,extracted 10 ml tube- sealing fluid each time and conducted pulsed positive pressure sealing once every 6 h. Observed indwelling time and vein- blocking condition of deep vein catheters of patients in both groups.Results： Experimental group patients had longer indwelling time and less catheter- blocking condition than control group. Both differences had statistical significance（ P〈 0. 05）. Conclusions： Using sodium bicarbonate and heparin sodium to seal deep vein can effectively prolong indwelling days of deep vein catheters and reduce their blocking rate.