潍坊市妊娠合并碘缺乏病筛查的意义及对胎儿结局的影响

Screening pregnant women with iodine deficiency disease and its effect on fetal outcome

目的探讨妊娠合并碘缺乏病的筛选对胎儿结局的影响。方法选择2008年4月~2014年5月潍坊市益都中心医院参加孕期保健的孕妇635例,对所有孕妇的临床资料做问卷调查分析,其中问卷调查表为自制,妊娠在5~12周进行尿碘筛查和B超检测,检测胎儿的生长发育情况,同时观察胎儿是否有出现畸形现象,对于新生儿进行甲状腺功能和听力的筛查。结果经调查结果分析,妊娠合并碘缺乏病的患病几率为4.2%左右,其中农村患病率为4.4%,城镇患病率为3.8%;在本次研究的635例孕妇中,碘营养为正常的孕妇有604例,在这604例孕妇中所怀胎儿为不良结局的有83例,表现为胎儿异常比例为13.7%;有31例表现为碘缺乏的孕妇所怀的胎儿中有17例为不良结局,胎儿异常的发生率为54.8%。结论给妊娠早期的孕妇进行尿碘的筛查,尤其是甲状腺肿大的孕妇,同时应该检测甲状腺的功能,对于轻、中度碘缺乏的孕妇在怀孕期间要多补充富含碘的食品或改变饮食习惯,重度碘缺乏的孕妇需要服用对胎儿安全的补碘药物。

Objective To investigate the screening of pregnant women with iodine deficiency disease,and the effect of fetal outcome.Methods The choice 2008Month^May 2014 period to our hospital to participate in maternal health care during pregnancy 635 cases,clinical data of all patients do questionnaire survey,in which the questionnaire was made pregnant in5~12weeks urinary iodine screening and B-test,to detect the growth and development of the fetus,the fetus while observing whether the abnormal situation occurs,for neonatal thyroid function and hearing screening.Results The analysis of the survey,the prevalence of iodine deficiency disorders in pregnancy with a probability of about 4.2%,of which 4.4%prevalence rate in rural areas,urban prevalence rate was 3.8%;in all pregnant women in this study,the iodine nutrition there are 604 cases of normal pregnant women,in which 604 cases of pregnant women conceived fetus adverse outcomes83 cases showed fetal abnormalities ratio of 13.7%;31cases showed iodine deficiency in pregnant women pregnant fetus planted with 17 cases of adverse outcomes,fetal abnormalities was 54.8%.Conclusion The early pregnancy pregnant women to urinary iodine screening,especially pregnant women goiter,thyroid function should be detected at the same time,for mild to moderate iodine deficiency during pregnancy to add more iodine-rich foods or changes in eating habits,severe iodine deficiency in pregnant women,need to take the fetus safe iodine drugs.