原发性高血压患者发病危险因素与性别的相关性

Study on correlation of risk factors and gender in patients with essential hypertension

目的探讨影响原发性高血压患者发病的危险因素与性别的相关性。方法选择原发性高血压患者共960例,根据性别分为男性、女性两组,对比两组患者相关危险因素。结论男、女两组对比显示,男性组仅父亲患高血压、吸烟率、饮酒率、丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、肌酐、尿酸显著高于女性组(P<0.05),女性组仅母亲患高血压、体质量指数、总胆固醇、三酰甘油、低密度脂蛋白、胱抑素C高于男性组(P<0.05),差异有统计学意义。结论男性与女性原发性高血压患者对比,其遗传因素及环境因素差异均有统计学意义。

Objective To investigate the risk factors of hypertension in patients with essential hypertension and its correlation with sex. Methods A total of 960 patients with essential hypertension were divided into two groups according to the sex, and the related risk factors, and compared the risk factors of the two groups. Results Comparison of the two groups showed that fe- male group whose only father suffering from hypertension, the rate of smoking and drinking, valley third transaminase, aspartate aminotransferase, creatinine, uric acid was significantly higher than those in female group （ P 〈 0. 05 ）. The group female whose only the mother suffering from hypertension, body mass index, total cholesterol, triglyceride, low density lipoprotein, Cystatin C was higher than the male group （ P 〈 0. 05 ）. There were significant differences. Conclusion There were significant differences in genetic and environmental factors between male and female patients with essential hypertension.