黄海棠乙酸乙酯部位的化学成分研究

Chemical Constituents of Ethyl Acetate Fraction from Hypericum ascyron

目的:研究黄海棠乙酸乙酯部位的化学成分。方法:采用硅胶柱层析等色谱方法对黄海棠进行分离纯化,通过分析其波谱数据和理化性质,从而鉴定化合物结构。结果:从黄海棠乙酸乙酯部位中分离鉴定了13个化合物,分别为:金丝桃苷(1)、大萼金丝桃素B(2)、大萼金丝桃素C(3)、1,7-二羟基呫吨酮(4)、2,3-二甲氧基呫吨酮(5)、1-hydroxy-7-methoxyxanthone(6)、芦丁(7)、山柰酚(8)、toxyloxanthone B(9)、槲皮素(10)、槲皮苷(11)、β-胡萝卜苷(12)、β-谷甾醇(13)。结论:其中,化合物2、3、6、9为首次从该植物中分离得到。

Objective：To study the chemical consituents of Hypericum ascyron. Methods：The constituents were isolated and purified by chromatography on silica gel;the structure of the compound was determined by MS and NMR spectral analysis. Results：On the basis of spectroscopic analysis and comparison with the reported data, they were identified as hyperoside （1）, hypercalin B （2）, hypercalin C （ 3 ）, 1,7-dihydroxyxanthone （4）, 2,3-dimethoxyxanthone （5）, 1 -hydroxy-7-methoxyxanthone （ 6 ）, rutin （ 7 ）, kaempferol （ 8 ）, toxyloxan- thone B （9）, quercetin（ 10）, quercitrin （ 11 ） ,β-daucosterol （ 12 ） and β-sitosterol （ 13 ）. Conclusion ： Compounds 2,3,6 and 9 are ob- tained from this plant for the first time.