唐古特白刺叶的化学成分研究

Chemical constituents from leaves of Nitraria tangutorum

目的对唐古特白刺Nitraria tangutorum叶的化学成分进行研究。方法采用溶剂萃取,反复硅胶柱色谱和制备液相色谱等方法进行分离纯化,根据理化性质及核磁数据鉴定化合物的结构。结果从唐古特白刺叶的95%乙醇提取物中分离得到9个化合物,分别鉴定为4-氧代-β-紫罗兰醇-β-D-吡喃葡萄糖苷（1）、（6R,9R）-3-氧代-α-紫罗兰醇-β-D-吡喃葡萄糖苷（2）、blumenyl Cβ-D-glucopyranoside（3）、blumenyl Aβ-D-glucopyranoside（4）、丁香树脂酚-4′-O-β-D-吡喃葡萄糖苷（5）、citrusin B（6）、nikoenoside（7）、2-苯乙基-O-β-D-吡喃葡萄糖苷（8）和吲哚-3-乙基-β-D-吡喃葡萄糖苷（9）。结论化合物1~9均为首次从该属植物中分离得到,其中,化合物9的13C-NMR数据为首次报道。

Objective To study the chemical constituents from the leaves of Nitraria tangutorum. Methods The chemical constituents were isolated by solvent extraction, repeated silica gel chromatography, and preparative-HPLC. Their structures were elucidated by physicochemical properties and 1H-NMR and 13C-NMR data. Results Nine compounds were isolated from the ethanol extract of the leaves of N. tangutorum and their structures were identified as 4-oxo-β-ionol β-D-glycopyranoside（1）,（6R,9R）-3-oxo-α-ionol β-D-glycopyranoside（2）, blumenyl C β-D-glucopyranoside（3）, blumenyl A β-D-glucopyranoside（4）, syringaresinol- 4′-O-β-D-glucopyranoside（5）, citrusin B（6）, nikoenoside（7）, 2-phenylethyl-β-D-glucopyranoside（8） and indole-3-ethyl-β-D-glucopyranoside（9）. Conclusion All the isolates are reported from the plants of Nitraria L. for the first time and the 13C-NMR data of compound 9 are also reported for the first time.