摘要
目的探讨原发性高血压患者的动脉硬化指数(AASI)与患者并发心律失常的的相关性。方法选择我院老年医学中心收治的230例确诊原发性高血压患者同时进行24h动态心电图及24h动态血压监测,分为AASI≥50%组(中位数)和AASI<50%组(中位数),通过统计两组患者24h动态心电图监测中发生心律失常的情况并进行组间比较。结果 AASI≥50%组患者的高血压病程(14.6±4.8)年、24h收缩压(158.2±11.6)mm Hg、24h舒张压(73.9±8.2)mm Hg均显著的高于AASI<50%组患者且差异均具有统计学意义(p<0.05);两组患者的BMI、TC、TG、HDL-C、LDL-C、吸烟率比较差异不具有统计学意义(p>0.05)。AASI≥50%组患者的SDNN(80.3±18.2)ms、SDNNI(42.6±5.2)ms、PNN50(7.3±4.1)%、SDANN(82.5±14.9)ms、RMSDD(19.8±8.1)ms低于AASI<50%组患者且差异均具有统计学意义(p<0.05)。AASI≥50%组患者的室性期前收缩、复杂性室性心律失常、房性期前收缩、复杂性房性心律失常、左室高电压发生率均显著高于AASI<50%组患者且差异均具有统计学意义(p<0.05)。结论原发性高血压患者的动脉硬化指数≥50%中位数患者的心律失常发生率显著增高,所以对于这一部分患者严控患者血压、改善心肌重构对于预防高血压所致心律失常具有重要意义。
Objective In patients with essential hypertension arteriosclerosis index (AASI) and patients with arrhythmia correlation. Methods Selected author department treated 230 patients diagnosed with essential hypertension were simultaneously 24h Holter and ambulatory blood pressure monitoring, the group divided into AASI ≥ 50% (median) and AASI〈50% group (median), by situation arrhythmia and Holter monitoring groups were compared in the two groups were statistical 24h. Results AASI≥50% of hypertensive patients duration of (14.6 ± 4.8) years, 24h SBP (158.2 ± 11.6)mmHg, 24h diastolic (73.9 ± 8.2)mmHg were significantly higher than AASI 〈50% of patients, and the differences were statistically significant (p〈0.05); two groups were BMI, TC, TG, HDL-C, LDL-C, smoking rate difference was not statistically significant (p〉 0.05). AASI ≥ 50% patients of SDNN (80.3 ± 18.2)ms, SDNNI (42.6 ± 5.2)ms, PNN50 (7.3 ± 4.1)%, SDANN (82.5 ± 14.9)ms, RMSDD (19.8 ± 8.1)ms below the AASI 〈50% of patients, and the differences were statistically significant (p〈0.05). AASI ≥ 50% group of patients with ventricular contraction before, complex ventricular arrhythmias, atrial contraction, complex atrial arrhythmias, left ventricular high voltage generation were significantly higher than AASI〈50% of patients and the differences were statistically significant (P〈0.05). Conclusions Patients with essential hypertension arteriosclerosis index was significantly increased incidence of arrhythmia in patients with median ≥50%, so for that strict control of blood pressure in some patients, improve cardiac remodeling induced arrhythmia for prevention of hypertension is important significance.
出处
《临床心电学杂志》
2015年第5期356-359,共4页
Journal of Clinical Electrocardiology
基金
2011年度安徽医科大学校级教学研究项目(jyxm201165)
关键词
高血压
老年
动态动脉硬化指数
心律失常
Hypertention
elderly
ambulatory arterial stiffness index
arrhythmia