脑出血患者急性期血压变异性与短期预后的关系

Relationship between blood pressure variability and short-term prognosis in patients with acute intracerebral hemorrhage

目的：探讨脑出血患者急性期血压变异性与其短期预后的关系。方法：动态监测24小时血压,计算血压变异度包括收缩压变异度和舒张压变异度。用MRS评分评价预后,分为预后良好和预后不良组。用单因素分析和Logistic回归处理数据。结果：（1）单因素分析提示患者在年龄、性别、血液学指标方面差异无统计学意义;在24小时收缩压、24小时舒张压、收缩压变异度和舒张压变异度方面统计学具显著性差异。（2）结果提示将24小时收缩压和24小时舒张压引入模型,则模型改变有统计学意义。Logistic回归提示24小时收缩压与脑出血的预后相关,OR值为0.945（95%CI 0.902~0.990）,总的预测准确率为80.3%,说明具有较高的可信度。结论：24小时收缩压是脑出血早期预后的影响因子。

Objective： To investigate the relationship between the variability of blood pressure and the short-term prognosis in patients with acute intracerebral hemorrhage.Methods：24h systolic blood pressure（SBP）,24 h diastolic blood pressure（DBP） were used to calculate the systolic blood pressure variability（SBPV） and diastolic blood pressure variability（DBPV）.At the time of discharge, the patients were followed up for modified-Rankin score（MRS score）,and the patients were divided into two groups（good prognosis and poor prognosis）,data was treated by single factor analysis and Logistic regression analysis. Results：（1）Single factor analysis indicated that there was no significant difference in age, gender and blood parameters, and the difference was statistically significant in 24 hours systolic blood pressure,24 hours diastolic blood pressure, systolic blood pressure variability and diastolic blood pressure variability.（2）The results suggest that the 24 h systolic and diastolic blood pressure were into the model, then change of the model has statistical significance.Logistic regression indicated that the 24 h systolic blood pressure was associated with the prognosis of cerebral hemorrhage, and the OR value was 0.945（0.902~0.990 95% CI）.Overall forecast accuracy was 80.3%.Shows that it has a high credibility. Conclusion：24hours systolic blood pressure is a Predictive factors affecting the prognosis of cerebral hemorrhage.