2014年登革热89例临床分析

Clinical analysis of 89 patients with Dengue fever in 2014

目的分析中山大学孙逸仙纪念医院急诊科2014年收治的登革热病例的临床特征，为登革热的早期诊治和提高疗效提供临床依据。方法对中山大学孙逸仙纪念医院急诊科2014年8月至11月收治的89例登革热患者的流行病学资料、临床表现、辅助检查资料、治疗及转归情况数据进行回顾性分析。结果本组收治的登革热患者以9-10月居多，且多集中在中心城区；以中老年患者居多；主要临床表现为发热，头痛，肌肉酸痛，部分患者伴皮疹、出血，白细胞、血小板下降，肝功能谷草转氨酶升高为主。采用非抗病毒的综合治疗全部患者均可治愈，无死亡病例。结论登革热是一种自限性疾病，患病后多休息、适当对症治疗均可治愈，提高全民素质、防蚊灭蚊是预防本病的关键。

Objective To summarize the clinical characteristics of patients with Dengue fever admitted in the Emergency Department of Sun Yat-sen Memorial Hospital of Sun Yat-sen University in 2014 so as to provide clinical evidence for early diagnosis and treatment of Dengue fever.Methods A retrospective study was done on the clinical data of 89 patients with Dengue fever treated from August 2014 to November 2014 in aspects of epidemiological data,clinical features,laboratory examinations,treatment and prognosis. Results The onset time of the Dengue fever was from September to October.Most of the patients lived in the central town,with majority the middle-age and old-age patients.The main clinical features were fever, headache,muscle soreness.Some cases were accompanied by rash,bleeding,the decrease of white blood cells and platelet count,the elevation of glutamic oxaloacetic transaminase activity.All of the patients were cured by combined treatment without antiviral therapy,with no death.Conclusions Dengue fever is a self-limited disease.With much rest and proper treatment,most of patients can be cured.The key to the prevention of Dengue fever is to strengthen comprehensive control measures such as health education and anti-mosquito.