Barrett食管内镜及病理分析

Analysis of Endoscopic and pathological characteristics of Barrett' Sesophagus

目的探讨Barrett食管的内镜及病理特点。方法对新疆维吾尔自治区人民医院2013年1月至2015年5月365例经胃镜检查、病理诊断的Barrett食管患者资料进行回顾性分析。结果 Barrett食管患者以40~60岁较多。临床症状与胃食管反流病有不同程度重叠,反酸278例（76.1%）,胃灼热171例（46.8%）,上腹痛167例（45.7%）,胸骨后疼痛77例（21%）,无症状49例（13.4%）。胃镜下可见岛型234例（64.1%）,舌型74例（20.2%）,全周型57例（15.6%）。病理分型：肠化腺型上皮98例（26.8%）,胃底腺型上皮134例（36.7%）,贲门腺型133例（36.4%）。结论 Barrett食管多见于中年人,临床表现主要为胃食管反流的症状,电子胃镜下以岛型最多见,病理类型以胃底腺型及贲门腺型为主。

Objective To investigate the endoscopic and pathological characteristics of Barrett esophagus（ BE）. Methods Clinical data of 365 patients who were diagnosed as having BE with endoscopy and pathology in People＇s Hospital of Xinjiang Uygur Autonomous Region,from January 2013 to May 2015,were retrospectively analyzed. Results BE was most commonly seen in patients of 40 to 60 years old. The clinical manifestations overlapped in different patients,Including regurgitation in 278（ 76. 1%）,heartburn in 171（ 46. 8%）,retrostemal pain in 77（ 21%）,upper abdominal pain in 167（ 45. 7%）,asymptomatic in 49（ 13. 4%）. Under electronic gastroscopy,appearance of Mashima type was investigated in 234 patients（ 64. 1%）,tongue type change was found in 74 patients（ 20. 2%）,and the remaining were whole-week type change（ 15. 6%）. The results of pathological changes showed that the normal squamous epithelium was replaced by intestinal epithelium（ 26. 8%）,gastric epithelium（ 36. 7%） and borderline epithelium（ 36. 4%）separately. Conclusion Barrett＇ s esophagus is mainly seen in middle age population. Majority of symptoms for these patients are expressed as GERD. Mozhima type＇ s appearance is the main finding in gastroscopy,gastric epithelium and borderline epithelium main change in pathology.