筋骨痛宁胶囊联合氨基葡萄糖治疗膝骨关节炎临床观察

Clinical Observation on the Treatment of Knee Osteoarthritis with Jingu Tongning Jiaonang(筋骨痛宁胶囊) Combining Glucosamine

目的:观察筋骨痛宁胶囊联合氨基葡萄糖治疗膝骨关节炎的临床疗效。方法:将90例膝骨关节炎患者随机分为治疗组和对照组,每组45例。对照组给予氨基葡萄糖口服治疗,治疗组在对照组治疗基础上加服筋骨痛宁胶囊,2组1个疗程均为3个月。观察2组临床疗效、VAS评分、Lysholm评分改善情况。结果:治疗组显效15例,有效23例,无效7例,总有效率为84.44%;对照组显效9例,有效21例,无效15例,总有效率为66.67%。2组比较,差异有统计学意义(P<0.05)。治疗后,治疗组VAS评分和Lysholm评分较治疗前有明显改善,差异有统计学意义(P<0.01);与对照组比较,差异有统计学意义(P<0.01或P<0.05)。结论:筋骨痛宁胶囊联合氨基葡萄糖治疗膝骨关节炎疗效良好,值得应用推广。

Objective：To observe the clinical curative effect of Jingu Tongning Jiaonang（筋骨痛宁胶囊）combining glucosamine in the treatment of knee osteoarthritis.Methods：Ninety cases of knee osteoarthritis were randomly divided into a treatment group and a control group,45 cases in each.The control group was orally given glucosamine,while the treatment group was treated with Jingu Tongning Jiaonang combining glucosamine,both group treated for 3 months as a course.Their clinical efficacy,VAS score and Lysholm score were observed.Results：In the treatment group,15 cases were markedly effective,23 cases were effective,and 7 cases were ineffective,the total effective rate being 84.44%;while in the control group,9 cases were markedly effective,21 cases were effective,and 15 cases were ineffective,the total effective rate being 66.67%.The difference between the two groups was statistically significant（P 〈0.05）.After treatment,the VAS score and the Lysholm score of the treatment group were significantly improved compared with those before treatment,and the difference was statistically significant（P 〈0.01）,while the difference was statistically significant（P 〈0.01 or P 〈0.05） compared with the control group.Conclusion：Jingu Tongning Jiaonang combining glucosamine has a good curative effect in the treatment of knee osteoarthritis,worthy of application and promotion.