他克莫司软膏联合窄谱中波紫外线治疗白癜风疗效和安全性分析

Effect and Safety Analysis of Tacrolimus Ointment Combined With Narrow-band Ultraviolet Ray in the Treatment of Vitiligo

目的分析他克莫司软膏联合窄谱中波紫外线治疗白癜风疗效和安全性。方法选取2012年10月~2015年12月我院收治的160例白癜风患者进行分组研究,按照计算机数字法分为对照组和治疗组,对照组80例患者单独给予他克莫司软膏治疗,治疗组80例患者在此基础上联合窄谱中波紫外线治疗,对两组临床治疗效果及安全性进行比较。结果治疗期间,两组患者均未出现明显不良反应,治疗组总有效率以及不同病变部位的总有效率均高于对照组,经比较,组间差异存在统计学意义（P〈0.05）。结论他克莫司软膏联合窄谱中波紫外线治疗白癜风疗效确切,安全性高广。

Objective To analysis of tacrolimus ointment combined with narrow-band ultraviolet ray treatment efficacy and safety of vitiligo. Methods Choose October 2012 to December 2015 160 vitiligo patients of our hospital group study, according to the method of computer digital divided into control group and treatment group, control group, 80 cases of patients with single give tacrolimus ointment treatment, treatment group, 80 cases of patients on the basis of this combined therapy with narrowband ultraviolet ray, compares two groups of clinical therapeutic effect andsafety. Results During the treatment, no obvious adverse reaction occurred in both groups, the treatment group total effective rate and total effective rate of the lesion site were higher than that of control group, by comparison, the differences between groups（P0.05）. Conclusion Tacrolimus ointment combined with narrow-band ultraviolet ray in the treatment of vitiligo curative effect, high safety.