两种麻醉方式在颅脑损伤手术中的临床观察

Clinical observation of two methods of anesthesia in traumatic brain injury surgery

目的：探讨两种不同麻醉方式在颅脑损伤手术中的麻醉效果。方法选取来宾市中医医院2011年3月至2014年12月收治的64例颅脑外伤患者作为研究对象，按照随机数字表法将所有患者分为对照组和观察组，对照组患者采取静吸复合麻醉，观察组患者采取全凭静脉麻醉，比较两组患者麻醉期间不同时间点的心率和平均动脉压变化情况及两组患者苏醒时间、自主呼吸恢复时间、拔管时间。结果对照组患者在不同时间点其心率和平均动脉压比较差异有统计学意义（ P﹤0.05），观察组患者不同时间点其心率和平均动脉压比较差异未见统计学意义（P﹥0.05）；两组患者自主呼吸恢复时间比较差异未见统计学意义（P﹥0.05），而在苏醒时间和拔管时间方面观察组患者显著低于对照组（ P﹤0.05）。结论全凭静脉麻醉在颅脑损伤患者手术治疗时其血流动力学未见明显变化，且苏醒时间和拔管时间短。

objective To investigate the effect of tWo different anesthesia on surgery of traumatic brain injury. Methods From March 2011 to December 2014,64 cases of brain trauma in traditional Chi-nese medicine hospital of laibin Were randomly divided into control group and observation group,the con-trol group Was given inhalation anesthesia,and the observation group Was given total intravenous anesthe-sia. The heart rate and mean arterial pressure changes in different point of time and during anesthesia re-covery time,recovery time of spontaneous breathing and extubation time Were compared. Results There Were significant differences in heart rate and mean arterial pressure at different time points in the control group（ P﹤0. 05 ）,and there Were no significant differences in heart rate or mean arterial pressure at dif-ferent time points in the observation group（ P﹥0. 05 ）;the spontaneous breathing recovery time had no significant difference betWeen the tWo groups（ P ﹥0. 05 ）,While the recovery time and extubation time Was significantly loWer in the observation group than those in the control group （ P ﹤ 0. 05 ）. Conclusions Total intravenous anesthesia during surgery in patients With brain injury treatment,has no significant hemodynamic change and short extubation time and recovery time.