磷酸肌酸钠治疗新生儿缺氧缺血性脑病合并心肌损伤

Clinical observation on neonatal hypoxic-ischemic encephalopathy combined with myocardial damage treated by phosphocreatine

目的：探讨磷酸肌酸钠在新生儿缺氧缺血性脑病合并心肌损伤治疗过程中的应用效果。方法对照组缺氧缺血性脑病合并心肌损伤新生儿给予临床常规治疗，研究组在常规治疗基础上加用磷酸肌酸钠，记录两组临床疗效。结果两组缺氧缺血性脑病合并心肌损伤新生儿经上述相应措施治疗后，研究组临床治疗总有效率（87.80%）显著高于对照组（68.29%），差异有统计学意义（P﹤0.05）。结论对缺氧缺血性脑病合并心肌损伤新生儿在常规治疗基础上加用磷酸肌酸钠有利于显著提高其临床疗效，保障患儿的生活质量及生命安全。

objective To investigate the application effect of phosphate sodium on neonatal hy-poxic-ischemic encephalopathy and myocardial injury. Methods Neonatal hypoxic-ischemic encepha-lopathy With myocardial injury in control group Were given routine clinical treatment,and the study group Were conducted muscle sodium phosphate on the basis of conventional therapy,the clinical efficacy of the tWo groups Were recorded. Results After treatment,the clinical total effective rate of the study group （87. 80%）Was significantly higher than that of the control group（68. 29%）,the difference Was statisti-cally significant（ P﹤0. 05 ）. Conclusions hypoxic-ischemic encephalopathy and myocardial injury in neonates treated by conventional therapy based on the use of sodium phosphate muscle can significantly improve its clinical efficacy,quality of life and protect the lives and safety of children.