蛋白尿与肾功能损伤对妊娠高血压综合征患者预后的影响

Effect of proteinuria and renal dysfunction on the prognosis of patients with PIH

目的研究蛋白尿与肾功能损伤对妊娠高血压综合征（妊高征）患者预后的影响。方法随机选取2013年3月至2014年3月接收的180例妊高征患者和30例正常妊娠临床患者作为研究对象，分别检测其尿蛋白定量、血清尿素氮、尿酸、肌酐、钙以及血压水平，并进行比较和分析。结果妊高征患者和正常妊娠患者相比较，其分娩时间提前，早产儿的发生率比较高，而且血清尿素氮、尿酸、肌酐以及血压水平明显高于正常分娩患者，差异有统计学意义（P〈0．05），钙含量和尿蛋白含量明显低于正常分娩患者，差异有统计学意义（P〈0．05）。结论蛋白尿和肾功能的变化受到妊高征患者预后的影响，在临床上有着一定的指导意义。

Objective To study the effect of proteinuria and renal dysfunction on prognosis of patients with PIH. Methods Randomly selected 180 cases of PIH hospital admutted from March 2013 to March 2014 period and 30 patients with clinically normal pregnancy as research subjects, respectively. The urine protein, serum urea nitrogen, uric acid, creatinine, calcium and blood pressure levels were compared and analyzed. Results PIH and normal pregnant patients compared to their delivery ahead of time, the incidence of preterm children is relatively high, and serum urea nitrogen, uric acid, creatinine, and blood pressure levels were significantly higher in patients with a normal delivery, there were signifi- cant differences（P 〈 0.05 ）, urinary calcium content and protein content was significantly lower than those in patients with normal birth, there were significant differences （P 〈 0. 05）. Conclusions Changes in proteinuria and renal function by af- fecting the prognosis of patients with PIH, has a certain clinical significance.