Bi-PAP无创呼吸机与持续低流量吸氧治疗COPD并Ⅱ型呼吸衰竭疗效分析

Analysis of the curative effect of Bi-PAP noninvasive ventilator and continuous low-flow oxygen on COPD complicated with type II respiratory failure

目的观察Bi—PAP无创呼吸机与持续低流量吸氧治疗COPD并Ⅱ型呼吸衰竭的临床疗效。方法将2013年7月至2014年7月收治的90例COPD并Ⅱ型呼吸衰竭患者分为两组，均行常规治疗＋BiPAP治疗，观察组在此基础上行持续低流量吸氧治疗，于治疗前及治疗后3个月测定患者FVC（肺活量）、FEV1（1s用力呼气容积）、FEV1／FVC、6MWD（6min步行距离）、SGRQ评分并比较。结果两组治疗后各项肺功能指标均获得提高，组内比较差异有统计学意义（P〈0．05）；组间治疗前比较差异无统计学意义（P〉0．05），治疗后观察组各项肺功能指标均高于对照组，差异有统计学意义（P〈0．05）。两组治疗后，6MWD提高、SGRQ评分降低，组内比较差异均有统计学意义（P〈0．05）；组间治疗前比较差异无统计学意义（P〉0．05），治疗后观察组6MWD高于对照组，SGRQ评分低于对照组，差异有统计学意义（P〈0．05）。结论Bi—PAP无创呼吸机与持续低流量吸氧治疗COPD并Ⅱ型呼吸衰竭可强化治疗效果，提高患者生活质量，且简单易行，借鉴价值较高。

Objective To observe the clinical curative effect of Bi-PAP noninvasive ventilation and continuous low-flow oxygen on COPD complicated with type II respiratory failure. Methods Ninety cases of patients with COPD com- plicated with type II respiratory failure admitted into the hospital from July 2013 to July 2014 were studied and divided into two groups. The two groups were treated with conventional therapy and BiPAP on the basis of which the observation group received continuous low-flow oxygen therapy. The patients＇ FVC（ forced vital capacity） , FEV1 （forced expiratory volume in 1 minutes）, FEV1/FVC, 6MWD （6min of walking distance） and SGRQ 3 months before and after the treatment were measured and compared. Results After the treatment, the pulmonary function indexes of the two groups were improved. Comparison within the groups was significant （ P 〈 0. 05 ） ; in terms of comparison between groups, the comparison before the treatment was not significant（ P 〉 0. 05 ）. After the treatment, the pulmonary function indexes of the observation group were higher than those of the control group and the comparison was significant（P 〈 0. 05 ）. After the treatment, 6MWD of the two groups increased while SGRQ score decreased and comparison within groups was significant（ P 〈 0.05 ） ; in term of comparison between groups before the treatment was not significant（ P 〉 0. 05 ）. After the treatment, 6MWD of the observation group was higher than that of the control group while SGRQ score was lower than that of the control group and there was significant difference （P 〈 0. 05 ）. Conclusions Bi-PAP noninvasive ventilator and continuous low-flow oxygen therapy in treatment of COPD complicated with type II respiratory failure can strengthen the curative effect and improve the patients＇ quality of life, which is simple and easy to operate and of high reference value.