1149例女性生殖道支原体感染检测及药敏结果分析

Analysis of female reproductive tract mycoplasma infection determination and drug sensitivity results in 1149 cases

目的了解江门市新会中医院就诊的女性生殖道支原体感染及药敏情况,为临床合理使用抗菌药物提供依据。方法收集江门市新会中医院门诊和病房女性就诊患者生殖道样本进行支原体检测并做药敏分析,观察其支原体感染及耐药情况。结果 1149例患者共检出支原体369例,总阳性率为32.11%。其阳性率构成比是解脲支原体(Uu)单一感染为73.17%,人型支原体(Mh)单一感染为10.57%,Uu+Mh混合感染为16.26%。≤20岁患者总阳性率最高,明显高于其他几个年龄段(P<0.01)。Mh感染和Uu+Mh感染对红霉素、罗红霉素、阿奇霉素等药的耐药率达80%以上。结论本地区女性患者支原体感染以Uu感染为主,其阳性率远高于Mh感染和Uu+Mh感染,而Mh感染和Uu+Mh感染的耐药率比较高。

Objective To understand the conditions of reproductive tract mycoplasma infection and drug sensitivity for the visited female patients in Xinhui tradlitional Chinese medicine hospital and to provide the basis of rational use for the antimicrobi-al drugs in the clinics. Methods The reproductive tract specimen of the female out-patients and in-patients was collected to make the determination of mycoplasma and analysis of drug sensitivity. The conditions of mycoplasma and drug resistance were observed in these patients. Results The 369 cases of mycoplasma were detected among all 1149 cases and the total positive rate was 32. 11% . The single infection of ureaplasma urealytium（Uu）was 73. 17% ,the single infection of mycoplasma hominis （Mh）was 10. 57% and mixed infection of Uu ＋ Mh was 16. 26% for the constituent ratios of positive rates. The total positive rate for patients of ≤20 ages was highest and apparently higher than other several age groups（P ﹤ 0. 01）. The drug resistance rates for erythromycin,roxithromycin and azithromycin were more than 80% in Mh infection and Uu ＋ Mh infection. Conclusion The mycoplasma infection of female patients in this area is mainly Uu infection and its positive rate apparently is higher than Mh infection and Uu ＋ Mh infection. The drug resistance rates of Mh infection and Uu ＋ Mh infection are higher.