少肌性肥胖研究进展

RESEARCH PROGRESS OF SARCOPENIA OBESITY

在老年人中能量摄入过多,身体活动下降,低级别的炎症,胰岛素抵抗以及身体里激素的变化可能会导致少肌性肥胖。起初少肌症被认为是年龄相关的肌肉质量减少所导致的,但是现在很清楚了,少肌症主要是肌肉质量和肌力的变化。我们建议利用肥胖结合少肌症即少肌性肥胖代替肥胖和肌肉质量来评估老年人的不良风险结果,少肌性肥胖应该进行大规模的研究。

Excess energy intake,physical inactivity,low- grade inflammation,insulin resistance and changes in hormonal milieu may lead to the development of so called ＇sarcopenic obesity＇. Sarcopenia was originally believed that the culprit of age- related muscle weakness was a reduction in muscle mass,but it is now clear that changes in muscle composition and quality are predominant. We propose that the risk of adverse outcomes is better estimated by considering jointly obesity and muscle strength rather than obesity and muscle mass and the term ＂sarcopenic obesity＂should be revisited.