甲状腺手术围术期抗溃疡药使用分析

Analysis of anti-ulcerative drug use in patients undergoing thyroid operation during perioperative period

目的调查甲状腺手术围术期预防性使用抗溃疡药情况。方法回顾性分析我院2013年1月至12月393例甲状腺手术患者围术期抗溃疡药使用情况,用Excel对数据进行分类统计。结果我院甲状腺手术围术期抗溃疡药使用率为21.6%,给药时机以术后给药(92.9%)为主,给药途径以静脉滴注(94.9%)为主,药物利用指数为1.41。其中质子泵抑制剂使用率为100%,品种以兰索拉唑(87.1%)为主。结论甲状腺手术围术期存在过度使用抗溃疡药现象。

Objective To investigate anti-ulcerative drug （AUD） utility in patients undergoing thyroid operation against stress ulcer （SU） during perioperative period. Methods A total of 393 patients undergoing arthroscopic operation during Jan. to Dec. 2013 in our hospital were recruited and retrospectively analyzed with Excel spreadsheet. Results Among 393 patients in the study, eighty-five patients （21.6%） used AUD （92.9% ） after operation, most （94.9%） were administered by intrave- nous, and drug utilization index（DUI） was 1.48. Eighty-seven point one patients used proton pump inhibitors （PPIs） in which lansoprazole was prescribed most. Conclusion PPIs were overused in patients undergoing thyroid operation.