阻塞性睡眠呼吸暂停低通气综合征及其干预治疗对心血管疾病的临床意义

Clinical Significance of OSAHS and Its Intervention Therapy on Cardiovascular Disease

已有多项临床和基础研究提出,阻塞性睡眠呼吸暂停低通气综合征作为多种心血管疾病的独立危险因素,可增加高血压、冠心病及心律失常等多种心血管系统疾病的患病率及病死率,成为近年来研究热点之一。其常引起持续性、难治性高血压、各种复杂性心律失常、急性冠状动脉综合征等,经鼻持续气道正压通气治疗后可明显提高血压达标率,降低心律失常及心绞痛的发生频率,长期治疗可改善患者预后。

A number of clinical and basic studies have discussed that,as independent risk factors for cardiovascular disease,obstructive sleep apnea-hypopnea syndrome may increase hypertension,coronary heart disease and arrhythmia,and other cardiovascular disease morbidity and mortality,and has become one of the hot topics in recent years. It often causes persistent and refractory hypertension,complex arrhythmias and acute coronary syndrome. After treatment with nasal continuous positive airway pressure,it can significantly improve the compliance rate of blood pressure,reduce the frequency of angina and arrhythmia and improve the prognosis of patients.