4Hyeon J Y, Hwang S, Kim H,et al. Accuracy of Diagnostic Meth- ods and Surveillance Sensitivity for Human Enterovirus, South Korea, 1999-2011[J]. Emerg in fect dis,2013,19(8) : 1268.
6Di B, Zhang Y, Xie H, et al. Circulation of Coxsackievirus A6 in hand-foot mouth disease in Guangzhou, 2010 2012 [J]. Virol J, 2014,11;157.
7Yang Q, Ding J,Cao J, et al. Epidemiological and etiological char- acteristics of hand, foot, and mouth disease in Wuhan,China from 2012 to 2013 :outbreaks of coxsackieviruses A10[J]. J Med Virol, 20.15,87(6) :954.
8Zhu FC, Meng FY, Li JX, et al. Efficacy, safety, and immunology of an inactivated alum adjuvant enterovirus 71 vaccine in children in China: a multicentre, randomized, double-blind, placebo-con- trolled,phase 3 trial[J]. Lancet,2013,381(9882) :2024.
9Michel HK. EV71 vaccines:a first step towards multivalent hand, foot and mouth disease vaccines [J]. Expert Rev Vaccines,2015, 14(3) :337.
2Shimizu H, Okuyama K, Hirai Y. Epidemic of hand, food and mouth disease in Kawasaki city, Japan [J]. Jpn J Infect Dis, 2005,58:330 - 331.
3Ma E, Chan KC, Cheng P, et al. The enterovirus 71 epidemic in 2008-public health implications for Hong Kong [ J ]. Int J Infect Dis,2010,14(9) :e775 -780.
4Onozuka D, Hashizume M. The influence of temperature and humidity on the incidence of hand, foot, and mouth disease in Japan [J]. Sci Total Env,2011,410(411 ) :119 - 125.
5Ma E, Lam T, Wong C, et al. Is hand, foot and mouth disease associated with meteorological parameters[ J]. Epidemiol Infect, 2010(138) :1779 - 1788.
7Chang LY, Lin TY, Huang YC,et al. Comparison of enterovirus 71 and coxsackievirus A16 clinical illnesses during the Taiwan enterovirus epidemic, 1998 [J]. Pediatri Infect Dis J, 1999,18 ( 12 ) : 1092 - 1096.
8Ooi EE, Phoon MC, Ishak B, et al. Seroepidemiology of human enterovirus 71, Singapore [ J ]. Emerg Infect Dis, 2002,8 (9) :995 -997.
9Huang SC, Hsu YW, Wang HC, Huang SW, Kiang D, Tsai HP, Wang SM, Liu CC, Lin KH, Su IJ, Wang JR. Appearance of intratypic recombination of Enterovirus 71 in Taiwan from 2002 to 2005. Virus Res, 2008, 131:250-259.
10Huang YP, Lin TL, Kuo CY, Lin MW, Yao CY, Liao HW, Hsu LC, Yang CF, Yang JY, Chen PJ, Wu HS. The circulation of subgenogroups B5 and C5 of enterovims 71 in Taiwan from 2006 to 2007. Virus Res, 2008, 137(2):206- 212.