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D-二聚体水平在类风湿关节炎中的临床意义 被引量:8

The clinical significance of D-dimer in rheumatoid arthritis
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摘要 目的探讨类风湿关节炎(RA)患者血中D-二聚体(DD)水平及其临床价值。方法选取无锡市人民医院住院的50例RA患者,正常对照组30例。收集检测临床及实验室指标,分析D-二聚体水平及其与RA患者实验室检查指标的相关性。结果 RA患者血D-二聚体增高的比例明显高于正常对照组(P<0.01),RA患者D-二聚体增高与RA其他实验指标有一定的相关性。结论 RA患者血D-二聚体水平明显升高,且与病情活动度的一些实验室敏感指标密切相关。提示凝血-纤溶系统激活可能在RA的病情发展中有重要意义。 Objective To investigate the clinical significance of D-dimer in rheumatoid arthritis.Methods The study group comprised 50 RA patients who were admitted in ward from wuxi People‘s HospitaL and 30 healthy controls.Collect the clinical data and laboratory indexes to investigate the clinical significance of D-dimer.Results The plasm level of D-dimer in RA patients was higher than in the healthy controls.There was positive correlation between D-dimer and other laboratory indexes.Conclusion The plasm level of D-dimer elevates in rheumatoid arthritis,and has positive correlation with other laboratory indexes.The research indicated that the coagulation-fibrinolytic system may have important significance in the The progression of the disease of rheumatoid arthritis.
作者 孙果 王春娥
出处 《中国实验诊断学》 2016年第4期603-604,共2页 Chinese Journal of Laboratory Diagnosis
关键词 关节炎 类风湿 D-二聚体 Arthritis Rheumatoid D-Dimer
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参考文献8

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