在生理学研究中如何正确估计样本含量

How to scientifically estimate sample size in physiological research

目的:引起生理学研究人员对样本含量估计重要性的认识。方法:论述样本含量估计的意义及存在的问题,介绍常用的样本含量估计方法以及获取其他样本含量估计方法的途径。结果:清楚地表述了估计样本含量必需明白的基本概念、前提条件,并通过实例给出了两种场合下所需样本含量的估计过程和结果。结论:在估计样本含量时,必须明确资料将选用何种统计分析方法处理,并且应满足有关的前提条件,才能得到正确的估计结果。

Objective： To bring about physiological researchers＇ attention of the importance of sample size estimation. Methods： The significance as well as the current problems of sample size estimation were illustrated and the commonly-used sample size estimation methods were introduced. Results： The basic concepts and necessary premises of sample size estimation were stated. The estimation processes and results under two different circumstances were elaborated in detail via examples. Conclusion： To attain the proper estimated sample sizes,the computation must satisfy the necessary premises which included the appropriate statistical analysis methods to be used.