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癌基因PARK7/DJ-1在肿瘤中的研究进展 被引量:2

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摘要 DJ-1是近年来发现的一种新的癌基因,其有抗氧化、抗凋亡等多种功能。DJ-1可通过抗氧化、抑制凋亡途径、拮抗抑癌基因、参与拮抗抗肿瘤药物作用等途径促进肿瘤的形成及转移。现已证实在多种肿瘤中DJ-1的表达都显著增高,但其表达水平及特点各不相同。探讨DJ-1在恶性肿瘤中的作用及分子机制可为肿瘤患者的治疗方案提供新的思路。
出处 《医学研究杂志》 2016年第5期6-9,共4页 Journal of Medical Research
基金 国家自然科学基金青年基金资助项目(81200104) 湖北省自然科学基金资助项目(2015CFB654)
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