冠心病心力衰竭患者血脂水平与预后相关性研究

The study on correlation of lipid levels and prognosis in patients with heart failure and coronary artery disease

目的探讨冠心病心力衰竭患者血脂水平与预后的相关性。方法选取2013年2月至2014年2月该院收治的55例冠心病心力衰竭患者(观察组)和55例冠心病心功能正常患者(对照组)。对两组患者的血脂水平与心功能的关系进行比较,并分析血脂水平与冠心病心力衰竭患者的预后相关性。结果观察组患者在三酰甘油(TG)、总胆固醇(TC)及高密度脂蛋白胆固醇(HDL-C)水平显著低于对照组,且差异有统计学意义(P<0.05);死亡组患者的TG、HDL-C水平均显著低于存活组,且差异均具有统计学意义(P<0.05),通过Spearman相关性分析,冠心病心力衰竭严重程度与TG及HDL-C水平呈负相关性(P<0.05)。结论在冠心病心力衰竭患者的临床治疗中,应重视对患者的血脂水平检测,并给予适宜的血脂水平干预,以提高患者的TG、HDL-C水平,有助于改善冠心病心力衰竭患者的预后及提高生存率。

Objective To investigate the correlation of lipid levels and prognosis in patients with heart failure and coronary artery disease.Methods 55 cases of patients（observation group）with heart failure and coronary artery disease and 55 cases of patients（control group）with coronary artery disease in our hospital were selected from February 2013 to February 2014.The blood lipid level and cardiac function were analyzed and compared,as well as the correlation of lipid levels and the prognosis of patients with heart failure and coronary artery disease.Results The TG,TC and HDL-C levels of patients in observation group were significantly lower than those in the control group,and the differences between groups were statistically significant（P〈0.05）;the TG and HDL-C levels of patients in death group were significantly lower than those in the survival group,and the differences between groups were statistically significant（P〈0.05）.By Spearman correlation analysis,the severity levels of heart failure and coronary artery disease showed a negative correlation with TG and HDL-C levels（P〈0.05）.Conclusion In the clinical treatment of patients with heart failure and coronary artery disease,doctors should pay attention to the detection of patients′blood lipid level and improve the patients′TG,HDL-C levels by giving appropriate intervention to lipid levels,which could help to improve the prognosis of patients with heart failure and coronary artery disease and improve survival rate.