雅司样梅毒疹

Framboesiform syphilide: a case report

报告1例以全身雅司样丘疹为主要表现的二期梅毒。患者女,47岁。全身散在斑丘疹1个月余。皮肤科检查：头部、颈部、躯干及四肢散在大小不一的圆形斑丘疹,直径5～20 mm,表面有血痂,周围有红晕,较易剥离,剥离后为湿润出血性糜烂面,基底潮红,轻微浸润,有轻压痛。快速血浆反应素试验（RPR）（＋）,滴度1∶2048,梅毒螺旋体颗粒凝集试验（TPPA）（＋）。诊断：二期梅毒。治疗：经苄星青霉素治疗后皮损基本消退。

A case of frambesia papules as the main clinical manifestation of secondary syphilis is reported. A 47-year-old female presented with scattered maculopapules all over the body for one month. Physical examination revealed scattered cir- cular maculopapules sized 5-20 mm-diameter on the head, neck, trunk and hmbs. Lesions were covered with easily stripped bloody scab, and surrounded by red areola. Hemorrhagic erosion appeared after removal of scab. The rash had flushing base with slight infiltration and mild tenderness. Rapid plasma reagin（RPR） titer was 1：2048, and treponema pallidum particle agglutination assay（TPPA） was positive, The diagnosis of secondary syphilis was made. After 4-week treatment with benzathine benzylpenicillin, the lesions almost completely disappeared.