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甲亢眼病大剂量糖皮质激素冲击加免疫抑制剂治疗效果分析 被引量:6

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摘要 目的探讨甲状腺功能亢进症(甲亢)眼病大剂量糖皮质激素冲击加免疫抑制剂治疗的临床效果。方法 96例甲亢眼病患者,随机分为A组(糖皮质激素口服)、B组(大剂量糖皮质激素冲击治疗)、C组(大剂量糖皮质激素冲击联合免疫抑制剂治疗),各32例。对比三组患者的临床治疗效果。结果治疗6个月后,C组治疗总有效率为90.6%(29/32),明显高于A、B组的56.3%(18/32)、62.5%(20/32),差异有统计学意义(P<0.05)。A、B、C组不良反应发生率分别为65.6%(21/32)、25.0%(8/32)、21.9%(7/32),A组不良反应发生率高于B、C组,差异有统计学意义(P<0.05);B组与C组不良反应发生率比较,差异无统计学意义(P>0.05)。结论大剂量糖皮质激素冲击加免疫抑制剂治疗甲亢眼病临床效果良好,不良反应发生率低,安全性高,值得临床推广应用。
作者 张威
出处 《中国实用医药》 2016年第11期126-127,共2页 China Practical Medicine
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