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血清前降钙素原在预测ICU发生院内感染中的应用 被引量:1

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摘要 目的 评估血清前降钙素原(PCT)在重症监护室中预测院内感染的临床价值。方法 回顾性分析入住ICU的重症患者111例,根据出院时诊断结果,按是否发生院内感染分为院感组(n=52)和非院感组(n=59)。记录诊断院内感染时间上最接近的PCT及白细胞(WBC)值。通过描绘ROC曲线来判断PCT对预测院内感染的价值,比较WBC和PCT在院内感染诊断中的价值。结果 院感组和非院感组间WBC值差异无统计学意义(P〉0.05),而组间PCT值差异有统计学意义(P=0.000);ROC曲线中WBC、PCT曲线下面积分别为(AUC=0.584,95%CI 0.477~0.692,P=0.127)和(AUC=0.717,95%CI 0.620~0.815,P=0.000)。当PCT值为0.81ng/mL时,所对应的最大Youden指数为0.57。结论 PCT对院内感染的预测较WBC更有优势,及时监测血清PCT可为院内感染的早期辅助诊断提供参考。
出处 《广东医学》 CAS 北大核心 2016年第9期1328-1329,共2页 Guangdong Medical Journal
基金 广东省梅州市科技计划项目(编号:2012B61)
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参考文献9

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