不同来源当归药材中二氧化硫残留量的检测

The sulfur dioxide residue detection ofRadix Angelicae Sinensisfrom different sources

目的:检测不同地区市售当归药材中二氧化硫残留量,为当归临床用药提供参考。方法:采用《中华人民共和国药典》(2010年版)收载的酸蒸馏碘滴定法,对广东、河南、甘肃、黑龙江四个地区不同级别售卖点当归进行二氧化硫残留量测定,运用空白试验校正对当归药材中二氧化硫残留量进行评价。结果:收集自广东、河南、甘肃、黑龙江四个地区的16批当归药材均存在二氧化硫残留现象,仅来源于黑龙江三甲医院的当归药材中二氧化硫残留量符合药典规定,为29.44mg/kg,其余来源当归药材中二氧化硫残留量普遍较高(大于150mg/kg)。结论:硫磺熏蒸作为传统的中药加工方法,目前在当归药材的防虫和美观方面应用广泛;四个地区当归药材均存在二氧化硫残留情况,且残留程度不一,二氧化硫残留量与地区及销售点级别无直接相关性。

Objective The sulfur dioxide residue of Radix Angelicae Sinensis which collected from different territories were measured to instruct buying medicine safety. Method The sulfur dioxide residue was detected with the method acid distillation iodine titration described in pharmacopoeia of China （2010）, and sulfur dioxide titration results were corrected with blank test. Result Our result showed that the medicinal materials collected from Henan, Guangdong, Gansu, Heilongjiang province varydegrees of sulfur dioxide residue. Only 1 samplecollected from top three hospital in Heilongjiang province showed qualifiedsulfur dioxide residue （29.44mg/kg） under national standard 150mg/kg. Conclusion Currently, the sulfur fumigation method is widely used for insect- resistant and aesthetics in processing of Radix Angelicae Sinensis. Our result shows that the sulfur dioxide residue of Radix Angelicae Sinensis is varying in different region and there is no direct correlation with the point of sale level.