8月~4岁儿童乙肝病毒表面抗原和抗体分析

Analysis of The Hepatitis B Virus Surface Antigen and Antibody to HBs Ag in August to 4 years old Children

目的了解陆良县﹤5岁儿童血清乙肝病毒表面抗原(Hepatitis B Virus Surface Antigen,HBs Ag)和乙肝病毒表面抗体(Antibody to HBs Ag,Anti-HBs)情况,为乙型肝炎(乙肝)病毒(Hepatitis B Virus,HBV)的防制提供依据。方法通过对陆良县十个乡镇按人口数分层整群抽样624名儿童,经过酶联免疫法检测血清HBs Ag和Anti-HBs,并统计分析。结果该年龄段Hep B(Hepatitis B Vaccine,Hep B)接种率为99.68%,Hep B1及时接种率为89.74%;HBs Ag阳性率为0.48%,Anti-HBs阳性率为75.48%,两指标的阳性率与地区和性别间差异无统计学意义。结论 Hep B1及时和全程接种是阻断HBV感染因素之一,Anti-HBs阳性率随着人群年龄呈现下降趋势。加强﹥3岁儿童Anti-HBs监测,对高危人群开展Hep B加强免疫。

Objective To study the drought-hit luliang county children under the age of five serum Hepatitis B Surface Antigen（Hepatitis B Virus get Surface Antigen, HBs Ag） and Hepatitis B Virus Surface Antibody（Antibody to HBs Ag, Anti-HBs）, for the Hepatitis B Virus（HBV）, Hepatitis B Virus comes, HBV provides the basis for the prevention of. Methods Through to the drought-hit luliang county ten towns by stratified cluster sampling, 624 children, population by enzyme-linked immunoassay detection of serum HBs Ag and Anti-HBs, and statistical analysis. Results The age Hep B（Hepatitis B Vaccine, Hep B vaccination rate was 99.68%, Hep B1 timely vaccination rate is 89.74%; HBs Ag positive rate was 0.48%, the Anti-HBs positive rate was 75.48%, positive predictive value of two indicators and district and there was no statistically significant difference between the sexes. Conclusion Hep B1 timely and vaccinations are blocking the HBV infection factor, Anti-HBs positive rate as populations age showed a trend of decline. Strengthen the Anti-HBs monitoring, after 3 years old children of high-risk groups to carry out the Hep B strengthen immunity.