摘要
目的:研究氨甲喋呤与米非司酮联合治疗异位妊娠的临床疗效。方法:收集2013年7月-2014年12月笔者所在医院收治的异位妊娠患者90例,分为A组(氨甲喋呤肌注)、B组(氨甲喋呤肌注联合米非司酮口服)、C组(氨甲喋呤妊娠囊穿刺注射联合米非司酮口服),每组30例,对比三组患者的治疗成功率、不良反应发生情况、血清β-h CG及包块直径变化。结果:A组患者治疗成功率、血清β-h CG下降率最低,包块直径最大,比较差异均有统计学意义(P<0.05);C组包块破裂发生率较B组高,比较差异有统计学意义(P<0.05)。结论:氨甲喋呤联合米非司酮疗效好,前者肌注、后者口服能减少包块破裂风险,安全性高。
Objective: To study the clinical effect of Methotrexate combined with Mifepristone in the treatment of ectopic pregnancy.Method: Ninety patients with ectopic pregnancy admitted to our hospital from July 2013 to December 2014 were divided into A group(with Methotrexate intramuscular injection), B group(with oral Mifepristone and Methotrexate intramuscular injection), C group(with Methotrexate pregnancy sac puncture injection combined with oral Mifepristone), 30 patients in each group.The changes of the treatment success rate, adverse reactions occur, serum beta-hCG and package diameter compared among the three groups.Result: The success rate and serum beta-hCG of A group was the lowest in the three groups, which masses had the highest diameter, the differences were statistically significant(P〈0.05) ; the rupture of C group was higher than that of B group, the difference was statistically significant(P〈0.05). Conclusion: Methotrexate combined with Mifepristone has a good curative effect, by intramuscular injection of the former and the oral of the latter can reduce the rupture risk, which referring to a high safety.
出处
《中外医学研究》
2016年第15期20-21,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
米非司酮
氨甲喋呤
异位妊娠
Mifepristone
Methotrexate
Ectopic pregnancy