通过互联网招募MSM的HIV新发感染及队列保持影响因素分析

Analysis on new HIV infection rate and factors related with maintenance of study cohort in men who have sex with men recruited through internet

目的探讨浙江省湖州市通过互联网招募的男男性行为人群（MSM）人类免疫缺陷病毒（HIV）的新发感染状况,同时分析队列保持的相关影响因素,为MSM艾滋病预防策略和措施的制订和调整提供科学依据。方法利用互联网QQ群招募研究对象,在基线调查后的6个月对MSM进行一次随访,随访的内容包括流行病学问卷调查和HIV抗体检测。结果随访时,MSM人群HIV新发感染率为8.6/100人年（95%CI：0~3.3）,梅毒新发感染率为6.8/100人年（95%CI：5.9~11.3）;多元logistic回归分析结果表明,在本地居住2年以上（RR=2.97,95%CI：1.68~5.25）、纯同性恋（RR=3.02,95%CI：1.73~5.26）、有固定的同性性伴（RR=2.12,95%CI：1.22~3.68）、与异性发生过性行为（RR=1.96,95%CI：1.05~3.69）、既往检测过艾滋病（RR=1.90,95%CI：1.09~3.30）是MSM 6个月队列保持的独立影响因素。结论湖州市通过互联网招募的MSM人群HIV新发感染率和队列保持率较高,在本地居住2年以上、纯同性恋、有固定的同性性伴、与异性发生过性行为、既往检测过艾滋病是MSM队列保持的影响因素。

Objective To understand the newhuman immunodeficiency virus（ HIV） infection rate of HIV and the factors related with the maintenance of study cohort in men who have sex with men（ MSM） and provide evidence for the development of AIDS intervention and prevention strategies in this population. Methods MSMwere recruited through internet. Followup,including questionnaire survey and HIV antibody test,was conducted 6 months after baseline survey for them. Results The followup found that the newHIV infection rate was 8. 6 /100 person-years（ 95% CI： 5. 9- 11. 3）. The results of multiple logistic regression analysis showed that local residence for ≥ 2 years（ RR = 2. 97,95% CI： 1. 68- 5. 25）,only homosex（ RR = 3. 02,95% CI： 1. 73- 5. 26）,regular homosexual partners（ RR = 2. 12,95% CI： 1. 22- 3. 68）,heterosex in previous 6month（ RR = 1. 96,95% CI： 1. 05- 3. 69）,receiving HIV test（ RR = 1. 90,95% CI： 1. 09- 3. 30） were significantly associated with the completion of the follow-up. Conclusion Compared with other area in China,the incidence rate of HIV and the maintenance rate of study cohort in MSMwere high in Huzhou. Local residence for≥ 2 years,only homosex,regular homosexual partners,heterosex in previous 6 month,receiving HIV test were the factors related with the maintenance of study cohort.