期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

脂肪因子CTRP3的认识及研究现状 被引量：3

Mini-review for adipokine CTRP3
下载PDF
导出
摘要 CTRP3是C1q肿瘤坏死因子相关蛋白家族中的一员,是新发现的脂肪因子。研究发现CTRP3在抗炎、代谢调控及减轻缺血损伤等方面发挥重要作用。本文就CTRP3的分子结构、表达、含量以及生物功能做一综述。 CTRP3 is a newly identified adipokine, which is a member of the Clq/TNF-related protein family. Research has shown that CTRP3 has anti-inflammatory, anti-ischemic and metabolic regulation properties. In this review we focused on the structure, tissue expression, content and biological functions of CTRP3.
作者 赵莎莎 高超 陶凌
机构地区 第四军医大学西京医院心血管内科
出处 《心脏杂志》 CAS 2016年第3期341-343,361,共4页 Chinese Heart Journal
基金 陕西省重点科技创新团队计划项目基金资助(2014KCT-19) 国家自然科学基金面上项目基金资助(81470478) 国家自然科学基金青年项目基金资助(81225001)
关键词 C1q/肿瘤坏死因子相关蛋白3 脂肪因子 代谢调控 抗炎 心肌保护 CTRP3 adipokines metabolic regulation anti-inflammatory myocardial preservation
分类号 R392.12 [医药卫生—免疫学]
  • 相关文献

参考文献12

  • 1Schaffler A, Bueehler C. CTRP family : linking immunity to metabo- lism [J]. Trends Endocrinol Metab, 2012, 23(4):194-204.
  • 2Peterson JM, Wei Z, Wong GW. Clq/TNF-related protein-3 (CTRP3), a novel adipokine that regulates hepatic glucose output [ J ]. J Biol Chem, 2010, 285 (51 ) :39691 - 39701.
  • 3Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, et al. Molecular, biochemical and functional characterizations of Clq/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combina- torial associations and metabolic functions [ J ]. Biochem J, 2008, 416(2) :161 -177.
  • 4Kopp A, Bala M, Buechler C, et al. Clq/TNF-related protein-3 represents a novel and endogenous lipopolysaccharide antagonist of the adipose tissue[J]. Eno/ogy, 2010, 151( 11 ):5267 -5278.
  • 5Choi KM, Hwang SY, Hong HC, et al. Implications of Clq/TNF- related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris [ J ]. Cardiovasc Dia- betol, 2014, 13:14.
  • 6Yoo HJ, Hwang SY, Hong HC, et al. Implication of progranulin and Clq/TNF-related protein-3 (CTRP3) on inflammation and ath- erosclerosis in subjects with or without metabolic syndrome [ J ]. PIoS one, 2013, 8(2) :e55744.
  • 7Compton SA, Cheatham B. CTRP-3: blocking a toll booth to obesity- related inflammation[J]. Endocrinology, 2010, 151 (11) :5095 -5097.
  • 8Kopp A, Bala M, Weigert J, et al. Effects of the new adiponectin paralogous protein CTRP-3 and of LPS on cytokine release from mon- ocytes of patients with type 2 diabetes mellitus[ J]. Cytokine, 2010, 49(1) :51 -57.
  • 9Hofmaun C, Chen N, Obermeier F, et al. Clq/TNF-related pro- tein-3 (CTRP-3) is secreted by visceral adipose tissue and exerts antiinflammatory and antifibrotic effects in primary human colonic fibroblasts [J]. Inflamm Bowel Dis, 2011, 17(12) :2462 -2471.
  • 10Choi KM, Hwang SY, Hong HC, et al. Clq/TNF-related protein-3 ( CTRP-3 ) and pigment epithelium-derived factor (PEDF) concen- trations in patients with type 2 diabetes and metabolic syndrome[ J]. Diabetes, 2012, 61 ( 11 ) :2932 - 2936.

同被引文献25

引证文献3

二级引证文献15

心脏杂志
2016年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部