2型糖尿病对乳腺癌妇女生命质量影响的研究

Research of influence by type 2 diabetes mellitus on quality of life in women with breast cancer

目的研究2型糖尿病对乳腺癌患者生命质量的影响。方法以欧洲癌症研究与治疗组织QOL量表C30(EORTC QLQ-C30)分析50例原发性乳腺癌患者(对照组)和50例2型糖尿病合并乳腺癌患者(观察组)的生命质量,调查5年内的总生存率与无病生存率,并进行比较。结果根据EORTC QLQ-C30评分可知,观察组的躯体功能、角色功能、认知功能、情绪功能、社会功能及总体健康状况评分均显著低于对照组的相应评分(P<0.05)。观察组5年内的总生存率与无病生存率显著低于对照组(P<0.05)。结论 2型糖尿病影响乳腺癌患者的生命质量,应采取慢性病综合管理措施以提高糖尿病合并乳腺癌患者的生命质量。

Objective To investigate research influence by type 2 diabetes mellitus on quality of life in breast cancer patients. Methods European organization for research and treatment of cancer QOL questionnaireC30（EORTC QLQ-C30） was applied to analyze quality of life in 50 patients with primary breast cancer（control group） and 50 type 2 diabetes mellitus patients with complicated breast cancer（observation group）. Their 5-year total survival rate and disease-free survival rate were researched and compared. Results The observation group had obviously lower EORTC QLQ-C30 scores of physical function, role function, cognitive function, emotion function, social function and general health condition than scores in the control group（P〈0.05）. The observation group also had much lower 5-year total survival rate and disease-free survival rate than the control group（P〈0.05）. Conclusion Due to influence by type 2 diabetes mellitus on quality of life in breast cancer patients, implement of comprehensive management measures for chronic disease is necessary for improving quality of life in patients with diabetes mellitus and breast cancer.