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兰索拉唑与奥美拉唑治疗活动期胃溃疡效果比较 被引量:4

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摘要 目的比较兰索拉唑与奥美拉唑治疗活动期胃溃疡的效果及血清抗氧化因子的影响。方法 140例活动期胃溃疡患者随机分为兰索拉唑组与奥美拉唑组各70例,兰索拉唑组予兰索拉唑口服,奥美拉唑组予奥美拉唑肠溶胶囊口服,8周后评定疗效。观察治疗前后的抗氧化因子水平的变化。结果兰索拉唑组总有效率为95.7%,高于奥美拉唑组的81.4%;腺体密度、黏膜厚度、腺管形态改善情况均优于奥美拉唑组;血清丙二醛(MDA)、内皮素-1(ET-1)显著低于奥美拉唑组,超氧化物歧化酶(SOD)、一氧化氮(NO)显著高于奥美拉唑组,组间差异均有统计学意义。结论兰索拉唑治疗活动期胃溃疡效果优于奥美拉唑,且溃疡愈合质量更好。
作者 史陈波
出处 《中国乡村医药》 2016年第11期3-4,共2页
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