生物反馈疗法对帕金森病患者生活质量的影响

Influence of biological feedback therapy on quality of life in patients with Parkinson's disease

目的探讨生物反馈疗法对帕金森病患者生活质量的影响。方法选取2013年10月~2014年10月解放军白求恩国际和平医院诊治的帕金森病患者54例,按照随机数字表法分为两组,对照组患者27例实施常规治疗,观察组患者27例实施生物反馈疗法治疗。于治疗前后行简明健康调查问卷（SF-36）评定、帕金森病统一评分量表（UPDRS）评定、日常生活能力量表（ADL）评定、生活质量综合评定问卷（GQOL-74）评定。比较两组患者的治疗效果。结果与治疗前比较,两组患者治疗后日常生活能力均大幅提升（P〈0.05）,ADL评分、SF-36评分（生理功能、生理职能、躯体疼痛、活力、情感职能、精神健康、社会功能、总体健康）、GQOL-74评分（心理功能、物质生活、躯体功能、社会功能、总体评分）均显著增加（P〈0.05）,而UPDRS评分（精神行为和情绪、日常生活能力、运动检查、治疗的并发症、修订的HOEHN＆YAHR分级、SCHWAB＆ENGLAND日常活动能力量表）均显著降低（P〈0.05）。观察组患者日常生活能力明显好于对照组（P〈0.05）,ADL评分、SF-36评分（生理功能、生理职能、躯体疼痛、活力、情感职能、精神健康、社会功能、总体健康）、GQOL-74评分（心理功能、物质生活、躯体功能、社会功能、总体评分）均明显高于对照组（P〈0.05）,UPDRS评分（精神行为和情绪、日常生活能力、运动检查、治疗的并发症、修订的HOEHN＆YAHR分级、SCHWAB＆ENGLAND日常活动能力量表）均明显低于对照组（P〈0.05）。结论生物反馈疗法可明显提高帕金森病患者的生活质量。

Objective To investigate influence of biological feedback therapy on quality of life in patients with Parkinson＇s disease. Methods From October 2013 to October 2014, in Bethune International Peace Hospital of PLA, 54 patients with Parkinson＇s disease were selected and divided into two groups, according to random number table, 27 patients received routine treatment were as control group, 27 patients received biological feedback therapy were as observation group. All patients evaluated by concise health survey questionnaire（SF-36）, unified Parkinson＇s disease rating scale（UPDRS）, activity of daily lifescale（ADL）, general quality of life inventory（GQOL-74） before and after treatment.Treatment effect was compared between two groups. Results Compared with before treatment, activity of daily life enhanced significantly（P〈0.05）, while ADL score, SF-36 score（physiological function, physical function, body pain, vitality, emotional function, mental health, social function, overall health）, GQOL-74 score（psychological function, material life, physical function, social function, overall score） increased significantly（P〈0.05）, UPDRS score（mental behavior and emotion, ability of daily living, motor examination, treatment of complications, revision of HOEHNYAHR grading, SCHWABENGLAND activities of daily living scale） decreased significantly after treatment in two groups（P〈0.05）. Ability of daily life in observation group was significantly better than control group（P〈0.05）, ADL score, SF-36score（physiological function, physical function, body pain, vitality, emotional function, mental health, social function,overall health）, GQOL-74 score（psychological function, material life, physical function, social function, overall score）were significantly higher than control group（P〈0.05）, while UPDRS score（mental behavior and emotion, ability of daily living, motor examination, treatment of complications, revision of HOEHNYAHR grading, SCHWABENGLAND activities of daily living scale） were significantly lower than control group（P〈0.05）. Conclusion Biological feedback therapy can significantly improve quality of life in patients with Parkinson＇s disease.