急性B淋巴细胞白血病患者生存质量及其影响因素分析

Analysis on life quality of patients with acute B-lymphocytic leukemia and its influence factors

目的探讨急性B淋巴细胞白血病患者生存质量状态,并分析其相关影响因素。方法选取2014年10月~2016年1月中国医科大学附属盛京医院诊治的78例急性B淋巴细胞白血病患者为观察组,并同时选取同龄的78例健康体检者为对照组,对两组患者的WHOQOL-100量表评分进行比较,并观察组中不同性别、年龄、文化程度、社会支持程度、疾病认知度、KBS评分及FAB分型患者的WHOQOL-100量表评分,同时采用Logistic分析观察组中上述因素与患者生存质量的关系。结果观察组的WHOQOL-100量表各个指标及总评分均低于对照组（P〈0.05）,且不同性别、年龄、文化程度、社会支持程度、疾病认知度、KBS评分及FAB分型患者的各个指标及总评分之间差异有统计学意义（P〈0.05）,Logistic分析显示,性别、年龄、文化程度、社会支持程度、疾病认知度、KPS评分及FAB分型均与患者的生存质量有密切的关系（P〈0.05）。结论急性B淋巴细胞白血病患者生存质量状态相对较差,且性别、年龄、文化程度、社会支持程度、疾病认知度、KPS评分及FAB分型均对此类患者的生存质量有较大的影响,应给予充分的重视。

Objective To investigate and observe the life quality state of patients with acute B-lymphocytic leukemia,and analyze its related influence fators. Methods From October 2014 to January 2016, in Shengjing Hospital Affiliated to China Medical University, 78 patients with acute B-lymphocytic leukemia were selected as observation group, at the same time, 78 healthy persons physical examination with the same age were selected as the control group. The WHOQOL-100 score of two groups were compared, and the WHOQOL-100 score of observation group with different gender, ages, education degree, social support degree, disease awareness, KBS score and FAB types were compared too,then the relationship between those fators of observation and life quality of patients were analyzed by the Logistic analysis. Results The each WHOQOL-100 score index and total score of observation group were lower than those of control group（P〈0.05）, and the each index and total score of observation group with different gender, ages, education degree, social support degree, disease awareness, KPS score and FAB types all had statistically significant differences（P〈0.05）, and the gender, ages, education degree, social support degree, disease awareness, KPS score and FAB types all had close relationship to the life quality of patients by the Logistic analysis（P〈0.05）. Conclusion The life quality state of patients with acute B-lymphocytic leukemia is worse, and the gender, ages, education degree, social support degree, disease awareness, KBS score and FAB types are all have greater influence for the life quality of the patients,so those fators should be paid more attention.