海南季节性移居的高血压患者降血压效果相关因素

The influencing factors of antihypertensive effect with the “seasonal migratory type” hypertension in Hainan

目的分析海南季节性移居高血压患者降血压效果相关因素,为气候、地域及生活习性所致的血压影响提供临床及理论依据。方法选择黑龙江省高血压患者328例作为研究对象,分为2012年10月到2013年4月在海南省儋州市期间居住177例作为A组,另外151例为2013年5月到9月在黑龙江生活期间的高血压患者作为B组。收集入选患者一般资料,采用非条件多因素Logistic回归方程计算影响季节性移居高血压患者降血压效果独立危险因素。结果 A组与B组年龄、体重指数、居住地、病程、饮酒、吸烟、并发症、家族史、每周运动时间等血压控制达标率差异具有统计学意义(P<0.05);且性别、居住地、饮酒史、吸烟史、合并并发症、有家族史、每周运动时间是影响高血压患者降压效果的独立危险因素。在相同药物治疗作用下,A组血压控制效果明显好于B组,差异具有统计学意义(P<0.05)。结论性别、居住地、饮酒史、吸烟史、合并并发症、有家族史、每周运动时间是影响高血压患者降压效果的独立危险因素。

Objective To explore the influencing factors of antihypertensive effect with the ＂seasonal migratory ＂hypertension in Hainan. Methods 328 hypertension patients in Heilongjiang Province were enrolled in the study; 177 cases lived in Danzhou Province（Oct 2012 to Apr 2013） as the seasonal migratory group, while 151 cases lived in Heilongjiang Province（May to Sep 2013） as non-seasonal migratory group. Clinical data were collected and analyzed by unconditional Logistic regression. Results Compared with non-seasonal migratory group, the control rate of age, body mass index, place of residence, course of disease, alcohol consumption, smoking, complications, family history,exercise time per week in seasonal migratory group were significantly better（P〈0.05）. The place of residence, drinking,smoking, complication, family history and exercise time per week were independent risk factors for antihypertensive effect. At the same drug treatment condition, the antihypertensive effect in the seasonal migratory group was significantly better than that in the non-seasonal migratory group（P 〈0.05）. Conclusion Gender, place of residence, drinking,smoking, complication, family history and exercise time per week were independent risk factors for antihypertensive effect.