探讨盐酸替罗非班在冠心病治疗中的安全性及价值

To Explore the Safety and Value of Tirofiban Hydrochloric in the Treatment of Coronary Heart Disease

目的：研究盐酸替罗非班治疗冠心病的疗效及安全性。方法选取我院2014年5月～2015年5月接诊的90例冠心病患者进行研究。按照随机数表法，随机均分为两组。对照组应用常规的经冠状动脉介入治疗，并给予患者低分子肝素。观察组在对照组的基础上，应用盐酸替罗非班进行治疗。治疗后，观察两组治疗的疗效及用药的不良反应。结果治疗后，观察组的发生率（95.56％）高于对照组（82.22％），差异有统计学意义（χ2=4.0500，P=0.0442）；不良反应发生率（2.22％）低于对照组（17.78％），差异有统计学意义（χ2=6.0494，P=0.0139）。结论盐酸替罗非班治疗冠心病，疗效显著，安全性高。

Objective To study the curative effect and safety of tiroifban hydrochloric for the treatment of coronary heart disease （CHD）.Methods From May 2014 to May 2015, 90 cases of patients with coronary heart disease （CHD） were studied and were divided into two groups at random,＆amp;nbsp;according to the random indicator method. Control group was used by the conventional percutaneous coronary intervention combined with low molecular weight heparin. Observation group, on the basis of control group, were treated with tirofiban hydrochloric. After treatment, to observe the curative effect and the adverse reactions of drug use of two groups and. Results After treatment, the incidence rate of observation group （95.56%） is higher than the control group （82.22%）, the difference was statistically signiifcant （χ2=4.050 0,P=0.044 2）. The incidence rate of adverse reactions （2.22%）, which was lower than the control group （17.78%）, the difference was statistically signiifcant （χ2=6.0494,P=0.013 9）.Conclusion Tiroifban hydrochloride for the treatment of coronary heart disease had significant curative effect and high safety.