创新科技和信息化时代血管外科研究领域的现状和展望

Current status and perspectives of researches in the field of vascular surgery in the era of innovation, technology and informatics

实验研究和临床研究在血管外科的发展中起重要推动作用,随着创新科技和信息化的高速发展,在血管外科研究领域机遇和挑战并存.本文概述了临床医学相关研究模式的推进,并从转化医学、比较效益研究、精准医学和大数据角度,阐述近几年血管外科研究在这些领域的研究进展,内容涵盖干细胞移植治疗肢体严重缺血的转化和临床研究;新材料、新器械及三维打印技术的应用;血管外科常见疾病的比较效益研究包括腹主动脉瘤及颈动脉疾病的开放手术和微创的腔内血管外科手术比较;下肢动脉闭塞性病变治疗中不同球囊支架材料的比较;基因多型性和药物动力学;基因异常与血管病变及有意义的使用数据.各类研究的根本目的都是更好地服务于人类健康.

Both basic and clinical researches play important roles in the advancement of vascular surgery.Along with the rapid progress in innovation,technology and informatics,chances and challenges are coexisting.We briefly described the evolution of the research models related to clinical medicine.From the perspective of translational medicine,comparative effectiveness research,precision medicine and big data,we reviewed the recent researches in the field of vascular surgery,which covers translational and clinical researches of stem cell transplantation for the treatment of critical limb ischemia;the application of new materials,devices,equipment and 3D printing;comparative studies of most common vascular diseases including open surgical versus minimally invasive endovascular treatment of abdominal aortic aneurysm,and carotid artery disease,as well as comparisons of efficacy of different balloons or stents used for the treatment of peripheral artery disease;gene polymorphism and pharmacodynamics;genetic abnormalities and vascular diseases.Regardless of the research,the ultimate purpose is to provide the better care to the human being.