摘要
重症肌无力(myasthenia gravis)是一种获得性自身免疫性疾病,一般认为发病年龄有2个高峰,分为早发型和晚发型。但近年临床资料显示,晚发型重症肌无力(late-onset myasthenia gravis,LOMG)的发病呈增高趋势。
出处
《实用医学杂志》
CAS
北大核心
2016年第10期1725-1726,共2页
The Journal of Practical Medicine
参考文献10
-
1ZIVKOVIC SA, CLEMENS PR. Char- acteristics of late-onset myasthenia gravis [J]. J Neurol, 2012,259(10): 2167-2171.
-
2CHUANG WY, STRBEL P, BOHLE- NDER-WILLKE AL, et al. Late-onset myasthenia gravis-CTLA4 (low) geno- type association and low-for-age thymic output of nave T ceils [J]. J Autoim- mun, 2014,52:122-129.
-
3SIVAKUMAR S. Current and emergingtreatments for the management of myas- thenia avis [J]. Ther Clin Risk Man- ag, 2011,7:313-323.
-
4张丽丽,赵欣欣,杨琦,闵睿,王宗谦.糖皮质激素对内毒素耐受的影响[J].实用药物与临床,2014,17(6):724-727. 被引量:2
-
5王勇,应秀娟.小剂量糖皮质激素布地奈德吸入在支气管哮喘治疗中的应用[J].实用药物与临床,2014,17(2):199-202. 被引量:54
-
6高晨,黄佳.北京等四城市2012年儿科糖皮质激素门诊处方合理用药抽样分析与比较[J].实用药物与临床,2014,17(9):1214-1218. 被引量:11
-
7SIEB JP. Myasthenia gravis: An update for the clinician [J]. Clin Exp Immunol,2014,175(3) :408-418.
-
8YI JS, DECROOS EC, SERS DB, et al. Prolonge-eell depletion in MuSK myasthenia gravis following rituximab treatment [J]. Muscle Nerve, 2013,48 (6) :992-993.
-
9JACK KL. A review of azathioprine-in- duced hepatotoxicity and myelosuppres- sion in myasthenia gravis [J]. Muscle Nerve, 2014,50(4) :719.
-
10WOLFE GI, SILVESTRI NJ. Treat- ment-refractory myasthenia gravis [J]. J Clin Neuromuseul Dis, 2014,15 (4) : 167-178.
二级参考文献37
-
1Rearte B,Landoni V,Laborde E,et al.Differential effects of glucocorticoids in the establishment and maintenance of endotoxin tolerance[J].Clin Exp Immunol,2010,159:208-216.
-
2Kristofor KE,Shigeki T,Farshid N,et al.Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cell[J].J Immunol,2009,183:298-309.
-
3Olivier J,Sandrine R,Natacha B,et al.Dendritic cells modulated by innate immunity improve collagen-induced arthritis and induce regulatory T cells in vivo[J].Immunology,2008,126:35-44.
-
4Glenn F,Evans,Zuckerman SH,et al.Glucocorticoid-dependent and independent mechanisms involved in lipopolysaccharide tolerance[J].Eur J Immunol,1991;21:1973-1979.
-
5Cabezon R,Ricart E,Espana C,et al.Gram-negative enterobacteria induce tolerogenic maturation in dexamethasone conditioned dendritic cells[J].PLoS One,2012,7:e52456.
-
6Randow F,Syrbe U,Meisel C,et al.Mechanism of endotoxin desen-sitization:involvement of interleukin 10 and transforming growth factor beta[J].J Exp Med,1995,181:1887-1892.
-
7Fang Z,Bogoljub C,Hongmei Li,et al.IL-10 deficiency blocks the ability of LPS to regulate expression of tolerance-related molecules on dendritic cells[J].Eur J Immuno,2012,42:1449-1458.
-
8Berg DJ,Kuhn R,Rajewsky K,et al.Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance[J].J Clin Invest,1995,96:2339-2347.
-
9Annane D,Bellissant E,Bollaert PE,et al.Corticosteroids in the treatment of severe sepsis and septic shock in adults:a systematic review[J].JAMA,2009,301:2362-2375.
-
10Niimi A,Matsumoto H,Mishima M. Eosinophilic airway disorders associated with chronic cough[J].{H}PULMONARY PHARMACOLOGY & THERAPEUTICS,2009,(02):114-120.
共引文献64
-
1刘宇宁.不同剂量布地奈德雾化吸入治疗小儿哮喘急性发作临床疗效的比较研究[J].临床合理用药杂志,2020,13(3):83-84. 被引量:2
-
2陈翔.关于糖皮质激素类药物的临床用药误区以及合理用药方法[J].今日健康,2016,15(11):93-93. 被引量:1
-
3闫圣杰.经气动雾化吸入沙丁胺醇联合高压氧对支气管哮喘患者症状改善及血清PCT、SCF、Eotaxin水平的影响[J].中国卫生工程学,2019,18(1):138-141. 被引量:4
-
4周建华,陈锋.基层医院国产布地奈德气雾剂联合茶碱缓释片治疗支气管哮喘的疗效探讨[J].当代医学,2014,20(20):138-139. 被引量:6
-
5姜兴,杨晓华.阿奇霉素静脉滴注联合布地奈德雾化吸入治疗支气管哮喘的效果观察[J].中国当代医药,2015,22(6):154-156. 被引量:6
-
6邵剑峰.糖皮质激素吸入治疗小儿哮喘的效果观察[J].中国卫生标准管理,2015,6(7):220-221. 被引量:4
-
7冯志华.茶碱缓释片与小剂量布地奈德联合治疗中度哮喘的效果分析[J].中国现代药物应用,2015,9(9):116-117.
-
8李勇.小剂量布地奈德粉吸入剂联合茶碱控释剂治疗轻度支气管哮喘疗效观察[J].中国伤残医学,2015,23(10):121-122. 被引量:3
-
9李心国.糖皮质激素在儿科疾病中的应用现状及合理性分析[J].北方药学,2015,12(9):166-167. 被引量:3
-
10谷艳春,杨蕾,奚望.中西药联合治疗儿童支气管哮喘疗效观察[J].中国中西医结合儿科学,2015,7(5):485-487. 被引量:4
同被引文献7
-
1中国重症肌无力诊断和治疗专家共识[J].中国神经免疫学和神经病学杂志,2011,18(5):368-372. 被引量:60
-
2杨维丽,黄志.免疫抑制剂在重症肌无力中的临床应用[J].儿科药学杂志,2016,22(2):56-59. 被引量:6
-
3仲星星,汤可娜,吴帅,蒋建明,管阳太.重症肌无力患者血脂异常与糖皮质激素敏感的相关性分析[J].临床神经病学杂志,2016,29(3):164-167. 被引量:5
-
4张巍.重用黄芪方联合免疫抑制剂对重症肌无力LRP4及BAFF-R表达的影响[J].四川中医,2016,34(7):105-107. 被引量:4
-
5刘云,郝洪军,高枫.早、晚发型重症肌无力患者临床特点对比研究[J].中风与神经疾病杂志,2016,33(7):616-619. 被引量:9
-
6刘云,刘冉,郝洪军,赵桂萍,高枫.重症肌无力患者血清学标志物检测及临床意义[J].中国现代神经疾病杂志,2016,16(10):678-683. 被引量:12
-
7李勇.短程大剂量糖皮质激素冲击联合其他免疫抑制剂治疗重症肌无力的疗效观察[J].实用临床医药杂志,2018,22(7):38-41. 被引量:12
二级引证文献4
-
1范树良.晚发型重症肌无力患者的临床特点及预后[J].医药前沿,2020,10(36):125-127.
-
2眭晨欢.丙种球蛋白联合糖皮质激素治疗重症肌无力的效果分析[J].常州实用医学,2021,37(2):85-87.
-
3何源源.免疫球蛋白联合糖皮质激素冲击疗法对重症肌无力患者血清AChR-Ab水平和临床症状的影响[J].中外医疗,2022,41(3):25-28. 被引量:3
-
4陈进,李磊,李开璇,张由美.短程大剂量糖皮质激素冲击联合其他免疫抑制剂治疗对重症肌无力患者不良反应及效果的影响分析[J].中外医疗,2023,42(9):28-31. 被引量:1
-
1殷鹏,阮晓敏,蒋志毅,司马国旗.声嘶为首发症状的晚发型重症肌无力1例[J].中国耳鼻咽喉头颈外科,2006,13(9):628-628.
-
2刘玉祯,李红霞,平阳,许凤全.晚发型重症肌无力的临床特点(附48例分析)[J].脑与神经疾病杂志,2004,12(3):225-225. 被引量:2
-
3万世鸿.3例重症肌无力合并胸腺瘤的外科治疗[J].现代医药卫生,2004,20(11):1013-1013.
-
4史树贵,李露斯,郑彩梅.肌萎缩侧索硬化的研究进展[J].重庆医学,2003,32(2):230-232. 被引量:1
-
5黄志勇,王武军,邹小明,杨锡耀,陈钢.Effect of thymectomy for 36 children with myasthenia gravis[J].Journal of Medical Colleges of PLA(China),1999,14(3):193-195.
-
6NEUROLOGICAL DISORDER[J].China Medical Abstracts(Internal Medicine),1998(3):183-188.
-
7金迪,李颖,付锦.Th17在重症肌无力发病机制中作用的研究进展[J].中国免疫学杂志,2014,30(9):1272-1274.
-
8姜功前,吉庆春,陈占军,宋静超,崔新征.22例重症肌无力合并胸腺瘤的手术治疗体会[J].中国实用神经疾病杂志,2010,13(23):28-29. 被引量:6
-
9NEUROLOGICAL DISORDER[J].China Medical Abstracts(Internal Medicine),1995,12(3):187-191.
-
10李霞,范玉新,季碧霞,张咸宁,朱定良,庚镇城.The association of different human leucocyte antigen-DQ with myasthenia gravis[J].Chinese Medical Journal,1998(9):34-34.