摘要
目的 :对比分析用米非司酮和妈富隆治疗围绝经期功能失调性子宫出血的临床效果。方法 :对近年来我院妇科收治的100例围绝经期功能失调性子宫出血患者的临床资料进行回顾性研究。我们将这100例患者随机分为米非司酮组和妈富隆组,每组各有50例患者。我院使用米非司酮对米非司酮组患者进行治疗,使用妈富隆对妈富隆组患者进行治疗。治疗结束后,比较两组患者治疗的效果以及治疗前后其E2(雌激素)的水平、LH(黄体生成素)的水平和FSH(血清促卵泡生成素)的水平。结果 :妈富隆组患者治疗的总有效率明显高于米非司酮组患者,其治疗后E2的水平、LH的水平和FSH的水平均明显低于米非司酮组患者,二者相比差异具有显著性(P<0.05)。结论 :与使用米非司酮相比,用妈富隆治疗围绝经期功能失调性子宫出血的效果更好,而且能有效地降低患者体内雌激素的水平。因此,妈富隆可作为临床上治疗围绝经期功能失调性子宫出血的首选药物。
to investigate peri menopausal dysfunctional uterine bleeding with mifepristone and Marvelon treatment effect. Select the method of the medical research from Department of gynaeeology and obstetrics of our hospital January 2014 to December 20t4 100 cases of perimenopausal dysfunctional uterine bleeding patients as the object of observation were divided into the control group and the experimental group, while the control group was treated with mifepristone, patients in the experimental group received Mama Fulong treatment, compared two groups of clinical curative effect. Results after treatment, the patients in the experimental group effective rate was 90%, and the control of patients in the treatment group the effective rate for 76% and patients in the experimental group after clinical treatment of estrogen （E2）, luteinizing prime （LH） and serum promoting follicle stimulating hormone （FSH） observation indexes were significantly better than the control group （P 〈 0.05）. Conclusion peri menopausal dysfunctional uterine bleeding patients received Marvelon treatment, the effectiveness and safety of clinical treatment is relatively higher, and clinical application value is obviously better than that of mifepristione.
