进展性脑卒中的临床特点及溶栓治疗的效果分析

The Clinical Characteristics of Progressive Stroke and the Effect of Thrombolytic Therapy

目的探讨进展性脑卒中的临床特点及溶栓治疗的效果。方法回顾性分析82例进展性脑卒中患者的临床资料,分析其临床特点,并将其分为观察组和对照组,对照组在发病6 h内进行首次溶栓,观察组在6-72 h内再次进行溶栓,比较临床疗效。结果两组治疗前和首次溶栓后神经功能缺损评分比较,差异无统计学意义（P〉0.05）;观察组第4 d、第14 d、第21 d神经功能缺损评分均低于对照组（P〈0.05）。治疗3周后,观察组总有效率（90.5%）高于对照组（65.0%）（P〈0.05）。结论进展性脑卒中是缺血性脑卒中的严重阶段,临床上必须了解其临床特点、发病诱因和新发症状,把握好溶栓时机,才能取得显著的临床疗效。

Objective To investigate the clinical characteristics and treatment of thrombolysis in stroke effect. Methods A retrospective analysis of the clinical data of 82 patients with progressive stroke patients, analyze their clinical features, and divided into observation group and control group, the control group in the incidence of 6 h for the first time in the observation group after thrombolytic therapy 6-72 h again thrombolytic therapy, the curative effect was compared. Results The two groups before and after treatment for the first time the nerve function defect score comparison, the difference was not statistically significant（P 〉0.05）, observation group 4 days, 14 days, 21 days of nerve function defect scores were lower than the control group（P 〈0.05）. After 3 weeks of treatment, the total effective rate of the observation group（90.5%） was higher than that in the control group（65.0%）（P〈0.05）. Conclusion Progressive stroke is the severe stage of ischemic stroke, patients must understand its clinical characteristics, predisposing factors and new symptoms, grasp the good time of thrombolytic therapy, in order to achieve remarkable clinical therapeutic effect.