中成药致肝损害的临床特点分析

Clinical Characteristics of Liver Injury Caused by Chinese Patent Medicine

目的探究中成药致肝损害的用药及临床特点。方法提取我院2011年4月-2014年10月中成药致肝损害的不良反应报告表,对其性别、年龄,药物类型、用药时间、剂量、给药途径、临床表现予以分析。结果中成药致肝损害女性患者居多;服用风湿、类风湿及乳腺病治疗药较普遍;临床表现胃肠道症状较多;肝损害与用药时间,剂量密切相关。结论患者运用中成药治疗,应增强药物指导,选择正规给药途径,合理控制用药时间及剂量,定期检查肝功能,以降低中成药致肝损害的发生率。

Objective To explore the drug and clinical characteristics of liver damage caused by traditional Chinese medicine. Methods Extract the table of adverse reaction of liver damage induced by Chinese patent medicine in our hospital form April 2011 to October 2014, their sex, age, type of drug, administration time, dose, route of administration, clinical manifestations be analyzed. Results Traditional Chinese patent medicine cause liver damage in female patients are in the majority, taking rheumatism, rheumatoid disease and breast disease treatment drugs are more common, clinical manifestations of gastrointestinal symptoms are more, liver damage was closely related to administration time and dose. Conclusion Patients with traditional Chinese patent medicine treatment, should enhance drug guidance, select the regular route of administration, reasonable control of the time and dose of medication, regularly check liver function, in order to reduce the incidence of liver damage caused by traditional Chinese medicine.