DNA倍体定量分析在细胞学诊断中的价值

Value of DNA double body quantitative analysis in cytological diagnosis

目的:探讨DNA倍体定量分析在细胞学诊断中的应用价值。方法:221例病理学检查标本分别进行常规细胞学检查和DNA倍体定量分析,比较两种检验方法的效果。结果:常规细胞学检出癌57例,可疑癌17例,癌及可疑癌共计74例,占检查病例的33.48%;DNA倍体分析查出癌68例,可疑癌49例,癌和可疑癌共计117例,占检查病例的52.94%,两者比较差异有统计学意义(P<0.05)。结论:DNA倍体定量检测敏感性高于常规细胞学检查。

Objective：To explore the application value of quantitative analysis of DNA ploidy in cytological diagnosis.Methods：221 cases of pathological examination specimen were examined by conventional cytology and DNA ploidy quantitative analysis,and the results of the two methods were compared.Results：The conventional cytology detected 57 cases with cancer,17 cases suspected cancer,a total of 74 cases cancers and suspected cancers,accounted for 33.48% of the 221 cases examined;DNA ploidy analysis detected 68 cases with cancer,49 cases suspected cancer,a total of 117 cases and suspected cancers,accounted for 52.94% of the 221 cases examined,the difference was statistical significance（P〈0.05）.Conclusion：The sensitivity of DNA ploidy detection is higher than that of conventional cytology.