摘要
目的对溃疡性结肠炎患者应用柳氮磺吡啶与美沙拉嗪治疗的效果进行对比研究。方法选取于2013年4月~2016年2月在我院接受治疗的溃疡性结肠炎患者108例,并随机分为对照组（53例）和实验组（55例）,对分别应用柳氮磺吡啶和美沙拉嗪治疗的临床疗效进行对照研究。结果实验组患者的显效率、治疗总有效率均高于对照组[63.64%、92.73%vs.37.74%、71.70%],不良反应发生率低于对照组[9.09%vs.28.30%],组间差异经t检验,有统计学意义（P〈0.05）。结论溃疡性结肠炎患者应用美沙拉嗪治疗的效果优于柳氮磺吡啶,安全有效。
Objective Effects of sulfasalazine and mesalazine in treatment of ulcerative colitis are to be comparatively studied. Methods Chose 108 patients with ulcerative colitis who were treated in hospital from April 2013 to February 2016 and separate them into control group（53 patients）and study group（55 patients）at random,and then compared clinical effects of Sulfasalazine and mesalazine between two groups. Results Patients’ explicit efficiency and treatment efficacy in study group were much higher than counterparts in control group [63.64%、92.73% vs. 37.74%、71.70%]. Besides,patients’ side-effect incidence in study group was much lower than that in control group [9.09% vs. 28.30%]. There was a differential between two groups and such a differential had statistic value according to T-Check（P 〈 0.05）. Conclusion Mesalazine is much more effective in treatment of ulcerative colitis with efficiency and safety than sulfasalazine.
出处
《中国卫生标准管理》
2016年第7期122-123,共2页
China Health Standard Management
